Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity

Dynamic post-translational modifications allow the rapid, specific, and tunable regulation of protein functions in eukaryotic cells. S-acylation is the only reversible lipid modification of proteins, in which a fatty acid, usually palmitate, is covalently attached to a cysteine residue of a protein...

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Detalles Bibliográficos
Autores principales: Brown, Robert W. B., Sharma, Aabha I., Villanueva, Miguel Rey, Li, Xiaomo, Onguka, Ouma, Zilbermintz, Leeor, Nguyen, Helen, Falk, Ben A., Olson, Cheryl L., Taylor, Joann M., Epting, Conrad L., Kathayat, Rahul S., Amara, Neri, Dickinson, Bryan C., Bogyo, Matthew, Engman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693859/
https://www.ncbi.nlm.nih.gov/pubmed/36364996
http://dx.doi.org/10.3390/pathogens11111245

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