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A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit

CONTEXT: Lead (Pb) smelting workers are exposed to high lead levels and its adverse health effects. Despite no biological role, regulatory bodies regard blood lead levels (BLL) ≤40 µg/dL as upper acceptable limit in occupationally lead exposed population. OBJECTIVE: To explore the differences in gen...

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Autores principales: Upadhyay, Kuldip, Viramgami, Ankit, Balachandar, Rakesh, Pagdhune, Avinash, Sen, Somnath, Sarkar, Kamalesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693964/
https://www.ncbi.nlm.nih.gov/pubmed/36438510
http://dx.doi.org/10.4103/ijcm.ijcm_756_21
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author Upadhyay, Kuldip
Viramgami, Ankit
Balachandar, Rakesh
Pagdhune, Avinash
Sen, Somnath
Sarkar, Kamalesh
author_facet Upadhyay, Kuldip
Viramgami, Ankit
Balachandar, Rakesh
Pagdhune, Avinash
Sen, Somnath
Sarkar, Kamalesh
author_sort Upadhyay, Kuldip
collection PubMed
description CONTEXT: Lead (Pb) smelting workers are exposed to high lead levels and its adverse health effects. Despite no biological role, regulatory bodies regard blood lead levels (BLL) ≤40 µg/dL as upper acceptable limit in occupationally lead exposed population. OBJECTIVE: To explore the differences in general health status of individuals with BLL ≤40 µg/dL and >40 µg/dL. METHODS: All workers (n = 803) of age >18 years employed in a Pb smelting plant were interviewed with a semi-structured questionnaire to obtain sociodemographics, occupational details, followed by detailed clinical examination. 5 ml of venous blood was collected and BLLs were determined as per standard NIOSH method using GF-AAS technic. A complete general health status was performed including hemoglobin and blood pressure (BP). RESULTS: About 47.7% of the participants exhibited high BLL (>40 µg/dL), while the rest 52.3% were identified to have ≤40 µg/dL. Both groups were grossly similar in the majority of demographic and occupational parameters. Interestingly, both groups had substantially higher fraction of workers with elevated BP. CONCLUSIONS: Lead exposed workers with BLL ≤40 µg/dL are at equal risk of health hazards as those with BLL >40 µg/dL. There is a need to revisit the current guidelines on the BLL for workers to protect from the hazards of chronic lead exposure.
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spelling pubmed-96939642022-11-26 A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit Upadhyay, Kuldip Viramgami, Ankit Balachandar, Rakesh Pagdhune, Avinash Sen, Somnath Sarkar, Kamalesh Indian J Community Med Original Article CONTEXT: Lead (Pb) smelting workers are exposed to high lead levels and its adverse health effects. Despite no biological role, regulatory bodies regard blood lead levels (BLL) ≤40 µg/dL as upper acceptable limit in occupationally lead exposed population. OBJECTIVE: To explore the differences in general health status of individuals with BLL ≤40 µg/dL and >40 µg/dL. METHODS: All workers (n = 803) of age >18 years employed in a Pb smelting plant were interviewed with a semi-structured questionnaire to obtain sociodemographics, occupational details, followed by detailed clinical examination. 5 ml of venous blood was collected and BLLs were determined as per standard NIOSH method using GF-AAS technic. A complete general health status was performed including hemoglobin and blood pressure (BP). RESULTS: About 47.7% of the participants exhibited high BLL (>40 µg/dL), while the rest 52.3% were identified to have ≤40 µg/dL. Both groups were grossly similar in the majority of demographic and occupational parameters. Interestingly, both groups had substantially higher fraction of workers with elevated BP. CONCLUSIONS: Lead exposed workers with BLL ≤40 µg/dL are at equal risk of health hazards as those with BLL >40 µg/dL. There is a need to revisit the current guidelines on the BLL for workers to protect from the hazards of chronic lead exposure. Wolters Kluwer - Medknow 2022 2022-10-10 /pmc/articles/PMC9693964/ /pubmed/36438510 http://dx.doi.org/10.4103/ijcm.ijcm_756_21 Text en Copyright: © 2022 Indian Journal of Community Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Upadhyay, Kuldip
Viramgami, Ankit
Balachandar, Rakesh
Pagdhune, Avinash
Sen, Somnath
Sarkar, Kamalesh
A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title_full A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title_fullStr A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title_full_unstemmed A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title_short A Comparative Health Assessment of Occupationally Lead Exposed Individuals with Blood Lead Levels Range across Upper Acceptable Limit
title_sort comparative health assessment of occupationally lead exposed individuals with blood lead levels range across upper acceptable limit
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693964/
https://www.ncbi.nlm.nih.gov/pubmed/36438510
http://dx.doi.org/10.4103/ijcm.ijcm_756_21
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