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Fast Screening of Protein Tyrosine Phosphatase 1B Inhibitor from Salvia miltiorrhiza Bge by Cell Display-Based Ligand Fishing

Salvia miltiorrhiza Bge is a medicinal plant (Chinese name “Danshen”) widely used for the treatment of hyperglycemia in traditional Chinese medicine. Protein tyrosine phosphatase 1B (PTP1B) has been recognized as a potential target for insulin sensitizing for the treatment of diabetes. In this work,...

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Detalles Bibliográficos
Autores principales: Bai, Xiaolin, Fan, Wenqin, Luo, Yingjie, Liu, Yipei, Zhang, Yongmei, Liao, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693971/
https://www.ncbi.nlm.nih.gov/pubmed/36431993
http://dx.doi.org/10.3390/molecules27227896