Cargando…

Formulation and Evaluation of Novel Additive-Free Spray-Dried Triamcinolone Acetonide Microspheres for Pulmonary Delivery: A Pharmacokinetic Study

This work aimed to establish a simple method to produce additive-free triamcinolone acetonide (TAA) microspheres suitable for pulmonary delivery, and therefore more simple manufacturing steps will be warranted. The spray-drying process involved the optimization of the TAA feed ratio in a concentrati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amran, Mohammed, Khafagy, El-Sayed, Mokhtar, Hatem I., Zaitone, Sawsan A., Moustafa, Yasser M., Gad, Shadeed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693995/ https://www.ncbi.nlm.nih.gov/pubmed/36365172 http://dx.doi.org/10.3390/pharmaceutics14112354

Ejemplares similares

Development of Novel pH-Sensitive Eudragit Coated Beads Containing Curcumin-Mesalamine Combination for Colon-Specific Drug Delivery
por: Heikal, Eman J., et al.
Publicado: (2023)

Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice
por: Mousa, Ibrahim A., et al.
Publicado: (2022)

Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers
por: Heikal, Eman J., et al.
Publicado: (2023)

Application of hydroxyapatite nanoparticles in development of an enhanced formulation for delivering sustained release of triamcinolone acetonide
por: Koocheki, Saeid, et al.
Publicado: (2011)

Triamcinolone acetonide acetate
por: Lu, Xiao, et al.
Publicado: (2011)

Development and validation of a simple method for the determination of triamcinolone acetonide in nasal spray
por: Alzeer, Haya S., et al.
Publicado: (2023)

Biopharmaceutical Study of Triamcinolone Acetonide Semisolid Formulations for Sublingual and Buccal Administration †
por: Márquez Valls, Marta, et al.
Publicado: (2021)

Pharmacokinetics and retinal toxicity of various doses of intravitreal triamcinolone acetonide in rabbits
por: Ye, You-Fan, et al.
Publicado: (2014)

Intra-Articular Slow-Release Triamcinolone Acetonide from Polyesteramide Microspheres as a Treatment for Osteoarthritis
por: Tellegen, Anna, et al.
Publicado: (2021)

Sterile endophthalmitis rates and particle size analyses of different formulations of triamcinolone acetonide
por: Dodwell, David G, et al.
Publicado: (2015)

Intravitreal Triamcinolone Acetonide in Von Hippel–Lindau Patient with Novel Mutation
por: Bunajem, Maryam, et al.
Publicado: (2020)

Brief Report: A Phase IIb Trial of a Novel Extended‐Release Microsphere Formulation of Triamcinolone Acetonide for Intraarticular Injection in Knee Osteoarthritis
por: Conaghan, Philip G., et al.
Publicado: (2017)

Design and In Vivo Pharmacokinetic Evaluation of Triamcinolone Acetonide Microcrystals-Loaded PLGA Microsphere for Increased Drug Retention in Knees after Intra-Articular Injection
por: Ho, Myoung Jin, et al.
Publicado: (2019)

Trabeculectomy with intraoperative retrobulbar triamcinolone acetonide
por: Kahook, Malik Y, et al.
Publicado: (2009)

Patients treated with intravitreal triamcinolone acetonide
por: Gallenga, Pier E, et al.
Publicado: (2008)

A novel formulation for radiotherapy-induced oral mucositis: Triamcinolone acetonide mucoadhesive film
por: Pakravan, Fahimeh, et al.
Publicado: (2019)

A randomized, phase IIa study to assess the systemic exposure of triamcinolone acetonide following injection of extended-release triamcinolone acetonide or traditional triamcinolone acetonide into both knees of patients with bilateral knee osteoarthritis
por: Kivitz, Alan, et al.
Publicado: (2019)

Intra-articular injection of triamcinolone acetonide releasing biomaterial microspheres inhibits pain and inflammation in an acute arthritis model
por: Rudnik-Jansen, Imke, et al.
Publicado: (2019)

Preparation and In vitro / In vivo characterization of spray dried microsphere formulation encapsulating 4-chlorocurcumin
por: Gogu, P. K., et al.
Publicado: (2010)

Uniform Suspension of the Clustered Triamcinolone Acetonide Particle
por: Sugimoto, Masahiko, et al.
Publicado: (2013)

Transdermal permeability of triamcinolone acetonide lipid nanoparticles
por: Qin, Zhenmiao, et al.
Publicado: (2019)

Development of Triamcinolone Acetonide Nanocrystals for Ocular Administration
por: Formica, María Lina, et al.
Publicado: (2023)

Intravitreal bevacizumab alone or combined with triamcinolone acetonide as the primary treatment for diabetic macular edema
por: Marey, Hatem M, et al.
Publicado: (2011)

The Efficacy of Functional Endoscopic Sinus Surgery Combined With Triamcinolone Acetonide Aqueous Nasal Spray for the Treatment of Chronic Rhinosinusitis
por: Hao, Zhongping, et al.
Publicado: (2022)

Influence of Surface-Modification via PEGylation or Chitosanization of Lipidic Nanocarriers on In Vivo Pharmacokinetic/Pharmacodynamic Profiles of Apixaban
por: Zaky, Mohamed F., et al.
Publicado: (2023)

Formulation and evalution of montelukast sodium - chitosan based spray dried microspheres for pulmonary drug delivery
por: Panchal, Rushi, et al.
Publicado: (2012)

Intraocular Pressure Following Intravitreal Injection of Triamcinolone Acetonide
por: Ansari, Ejaz A, et al.
Publicado: (2008)

Effects of triamcinolone acetonide on vessels of the posterior segment of the eye
por: Valamanesh, Fatemeh, et al.
Publicado: (2009)

Delivery of Intraocular Triamcinolone Acetonide in the Treatment of Macular Edema
por: Pickrell, Aaron, et al.
Publicado: (2012)

Alopecia Areata—Successful Outcome with Microneedling and Triamcinolone Acetonide
por: Chandrashekar, BS, et al.
Publicado: (2014)

Lidocaine Potentiates the Deleterious Effects of Triamcinolone Acetonide on Tenocytes
por: Yang, Shu-long, et al.
Publicado: (2014)

Triamcinolone Acetonide-Assisted Descemetectomy for Retained Descemet Membrane
por: Tyring, Ariel, et al.
Publicado: (2018)

Anaphylaxis following intralesional triamcinolone acetonide (Kenacort) injection
por: Laisuan, Wannada, et al.
Publicado: (2017)

Successful treatment of acanthoma fissuratum with intralesional triamcinolone acetonide
por: Ramroop, Shivaughn
Publicado: (2020)

Extralesional triamcinolone acetonide injection in the treatment of small chalazion
por: Gan, Lu, et al.
Publicado: (2023)

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study
por: Conaghan, Philip G., et al.
Publicado: (2018)

Safety and Systemic Exposure of Triamcinolone Acetonide Following Ultrasound-Guided Intra-Articular Injection of Triamcinolone Extended-Release or Standard Triamcinolone Acetonide in Patients with Shoulder Osteoarthritis: An Open-Label, Randomized Study
por: Hanson, Peter, et al.
Publicado: (2021)

Preparation and properties of chitosan‐based microspheres by spray drying
por: Zhang, Zeng‐liang, et al.
Publicado: (2020)

Intralesional and sublesional injection of triamcinolone acetonide for oral lichen planus.
por: Sleeper, H. R.
Publicado: (1967)

Residual triamcinolone acetonide at macular hole after vitreous surgery
por: Goel, Neha, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_i1q1tue40duai3ha0pd788fukp