Cargando…

Investigating the Leishmania donovani sacp Gene and Its Role in Macrophage Infection and Survival in Mice

The protozoan parasite Leishmania donovani is a causative agent of the neglected tropical disease known as visceral leishmaniasis, which can be lethal when untreated. Studying Leishmania viru-lence factors is crucial in determining how the parasite causes disease and identifying new targets for trea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paulini, Kayla, Lypaczewski, Patrick, Zhang, Wen-Wei, Perera, Dilhan J., Ndao, Momar, Matlashewski, Greg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694005/ https://www.ncbi.nlm.nih.gov/pubmed/36422936 http://dx.doi.org/10.3390/tropicalmed7110384

Ejemplares similares

An intraspecies Leishmania donovani hybrid from the Indian subcontinent is associated with an atypical phenotype of cutaneous disease
por: Lypaczewski, Patrick, et al.
Publicado: (2022)

Evidence that a naturally occurring single nucleotide polymorphism in the RagC gene of Leishmania donovani contributes to reduced virulence
por: Lypaczewski, Patrick, et al.
Publicado: (2021)

Production of leishmanin skin test antigen from Leishmania donovani for future reintroduction in the field
por: Dey, Ranadhir, et al.
Publicado: (2023)

A complete Leishmania donovani reference genome identifies novel genetic variations associated with virulence
por: Lypaczewski, Patrick, et al.
Publicado: (2018)

CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani
por: Zhang, Wen-Wei, et al.
Publicado: (2015)

Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients
por: Zhang, Wen-Wei, et al.
Publicado: (2018)

A review of the leishmanin skin test: A neglected test for a neglected disease
por: Carstens-Kass, Jessica, et al.
Publicado: (2021)

Optimized CRISPR-Cas9 Genome Editing for Leishmania and Its Use To Target a Multigene Family, Induce Chromosomal Translocation, and Study DNA Break Repair Mechanisms
por: Zhang, Wen-Wei, et al.
Publicado: (2017)

Promising Technologies in the Field of Helminth Vaccines
por: Perera, Dilhan J., et al.
Publicado: (2021)

Recent Advances in the Development of Adenovirus-Vectored Vaccines for Parasitic Infections
por: Koger-Pease, Cal, et al.
Publicado: (2023)

Genetic Analysis of Leishmania donovani Tropism Using a Naturally Attenuated Cutaneous Strain
por: Zhang, Wen Wei, et al.
Publicado: (2014)

Leishmania donovani-Induced Increase in Macrophage Bcl-2 Favors Parasite Survival
por: Pandey, Rajeev Kumar, et al.
Publicado: (2016)

Hemophagocytosis induced by Leishmania donovani infection is beneficial to parasite survival within macrophages
por: Morimoto, Ayako, et al.
Publicado: (2019)

Leishmania donovani persistence and circulation causing cutaneous leishmaniasis in unusual-foci of Nepal
por: Rai, Tinmaya, et al.
Publicado: (2023)

Mobile suitcase laboratory for rapid detection of Leishmania donovani using recombinase polymerase amplification assay
por: Mondal, Dinesh, et al.
Publicado: (2016)

MHCA with SACP versus DHCA in Pediatric Aortic Arch Surgery: A Comparative Study
por: Xie, Ling, et al.
Publicado: (2020)

Salmonella Typhimurium expressing chromosomally integrated Schistosoma mansoni Cathepsin B protects against schistosomiasis in mice
por: Hassan, Adam S., et al.
Publicado: (2023)

Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages
por: Arish, Mohd, et al.
Publicado: (2018)

Leishmania Donovani. Hamster macrophage interactions in vitro: cell entry, intracellular survival, and multiplication of amastigotes
por: Chang, K-P, et al.
Publicado: (1978)

Linoleic Acid Inhibits the Release of Leishmania donovani Derived Microvesicles and Decreases Its Survival in Macrophages
por: Saini, Sheetal, et al.
Publicado: (2020)

Vaccination against the digestive enzyme Cathepsin B using a YS1646 Salmonella enterica Typhimurium vector provides almost complete protection against Schistosoma mansoni challenge in a mouse model
por: Hassan, Adam S., et al.
Publicado: (2019)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Linking In Vitro and In Vivo Survival of Clinical Leishmania donovani Strains
por: Vanaerschot, Manu, et al.
Publicado: (2010)

Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes
por: Boitz, Jan M., et al.
Publicado: (2016)

A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice
por: Perera, Dilhan J., et al.
Publicado: (2022)

Correction: Vaccination against the digestive enzyme Cathepsin B using a YS1646 Salmonella enterica Typhimurium vector provides almost complete protection against Schistosoma mansoni challenge in a mouse model
por: Hassan, Adam S., et al.
Publicado: (2021)

Deletion of Glutamine Synthetase Gene Disrupts the Survivability and Infectivity of Leishmania donovani
por: Kumar, Vinay, et al.
Publicado: (2021)

The role of PD-1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani
por: Roy, Shalini, et al.
Publicado: (2017)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

A Genomic-Based Approach Combining In Vivo Selection in Mice to Identify a Novel Virulence Gene in Leishmania
por: Zhang, Wen-Wei, et al.
Publicado: (2008)

Intracellular Pathogen Leishmania donovani Activates Hypoxia Inducible Factor-1 by Dual Mechanism for Survival Advantage within Macrophage
por: Singh, Amit Kumar, et al.
Publicado: (2012)

Innate Killing of Leishmania donovani by Macrophages of the Splenic Marginal Zone Requires IRF-7
por: Phillips, Rebecca, et al.
Publicado: (2010)

Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages
por: Marr, Alexandra K., et al.
Publicado: (2014)

In vitro permissiveness of bovine neutrophils and monocyte derived macrophages to Leishmania donovani of Ethiopian isolate
por: Tasew, Geremew, et al.
Publicado: (2016)

Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages
por: Voak, Andrew A, et al.
Publicado: (2018)

Impact of Leishmania donovani infection on the HLA I self peptide repertoire of human macrophages
por: Nyambura, Lydon Wainaina, et al.
Publicado: (2018)

Role of cAMP Signaling in the Survival and Infectivity of the Protozoan Parasite, Leishmania donovani
por: Biswas, Arunima, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_1opql089vjdt818hblkfe22uab