Cargando…

Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors

Cofactor flavin adenine dinucleotide (FAD), a compound with flavin moiety and a derivative of riboflavin (vitamin B(2)), is shown to bind to Sox9 (a key transcription factor in early pancreatic development) and, subsequently, induce a large increase in markers of pancreatic development, including Ng...

Descripción completa

Detalles Bibliográficos
Autores principales:	Islam, Zeyaul, Aldous, Noura, Choi, Sunkyu, Schmidt, Frank, Mifsud, Borbala, Abdelalim, Essam M., Kolatkar, Prasanna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694089/ https://www.ncbi.nlm.nih.gov/pubmed/36430529 http://dx.doi.org/10.3390/ijms232214051

Ejemplares similares

Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis
por: Moreno, Andrea, et al.
Publicado: (2021)

Loss of flavin adenine dinucleotide (FAD) impairs sperm function and male reproductive advantage in C. elegans
por: Yen, Chia-An, et al.
Publicado: (2020)

Flavin Adenine Dinucleotide Rescues the Phenotype of Frataxin Deficiency
por: Gonzalez-Cabo, Pilar, et al.
Publicado: (2010)

Why the Flavin Adenine Dinucleotide (FAD) Cofactor Needs To Be Covalently Linked to Complex II of the Electron‐Transport Chain for the Conversion of FADH(2) into FAD
por: Dourado, Daniel F. A. R., et al.
Publicado: (2017)

Role of Key Residues at the Flavin Mononucleotide (FMN):Adenylyltransferase Catalytic Site of the Bifunctional Riboflavin Kinase/Flavin Adenine Dinucleotide (FAD) Synthetase from Corynebacterium ammoniagenes
por: Serrano, Ana, et al.
Publicado: (2012)

pH-Dependent Flavin Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Ultraviolet Resonance Raman (UVRR) Spectra at Intracellular Concentration
por: Merk, Virginia, et al.
Publicado: (2021)

Flavin Adenine Dinucleotide Structural Motifs: From Solution to Gas Phase
por: Molano-Arevalo, Juan Camilo, et al.
Publicado: (2014)

Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases
por: Niwa, Hideaki, et al.
Publicado: (2017)

Calculation of the Geometries and Infrared Spectra of the Stacked Cofactor Flavin Adenine Dinucleotide (FAD) as the Prerequisite for Studies of Light-Triggered Proton and Electron Transfer
por: Kieninger, Martina, et al.
Publicado: (2020)

Flavin Adenine Dinucleotide (FAD) Pegylated (PEG)-Complexes: Proof of Concept (PoC) of theranostic tool on a Murine Breast Cancer Model
por: Arib, Celia, et al.
Publicado: (2022)

Characterisation of the flavin adenine dinucleotide binding region of Myxococcus xanthus protoporphyrinogen oxidase
por: Boateng, Mavis O., et al.
Publicado: (2015)

Straightforward Regeneration of Reduced Flavin Adenine Dinucleotide Required for Enzymatic Tryptophan Halogenation
por: Ismail, Mohamed, et al.
Publicado: (2019)

Flavin Adenine Dinucleotide-Related Adverse Event Necessitating Cardiopulmonary Resuscitation in an Infant
por: Fujii, Shunsuke, et al.
Publicado: (2022)

Flavin Adenine Dinucleotide Fluorescence as an Early Marker of Mitochondrial Impairment During Brain Hypoxia
por: Berndt, Nikolaus, et al.
Publicado: (2020)

Revealing the transient conformations of a single flavin adenine dinucleotide using an aerolysin nanopore
por: Li, Meng-Yin, et al.
Publicado: (2019)

Predicting Flavin and Nicotinamide Adenine Dinucleotide-Binding Sites in Proteins Using the Fragment Transformation Method
por: Lu, Chih-Hao, et al.
Publicado: (2015)

Flavin adenine dinucleotide-capped gold nanoclusters: biocompatible photo-emissive nanomaterial and reservoir of lumichrome
por: Pérez-Herráez, Irene, et al.
Publicado: (2022)

Identification of Diosmin and Flavin Adenine Dinucleotide as Repurposing Treatments for Monkeypox Virus: A Computational Study
por: Lam, Thua-Phong, et al.
Publicado: (2022)

Thermophilic Talaromyces emersonii Flavin Adenine Dinucleotide-Dependent Glucose Dehydrogenase Bioanode for Biosensor and Biofuel Cell Applications
por: Iwasa, Hisanori, et al.
Publicado: (2017)

Flavin-adenine-dinucleotide gold complex nanoparticles: chemical modeling design, physico-chemical assessment and perspectives in nanomedicine
por: Arib, Celia, et al.
Publicado: (2021)

Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2
por: Tramonti, Angela, et al.
Publicado: (2021)

A Pegylated Flavin Adenine Dinucleotide PEG Complex to Boost Immunogenic and Therapeutic Effects in a Liver Cancer Model
por: Arib, Celia, et al.
Publicado: (2021)

Correction: Flavin-adenine-dinucleotide gold complex nanoparticles: chemical modeling design, physico-chemical assessment and perspectives in nanomedicine
por: Arib, Celia, et al.
Publicado: (2023)

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism
por: Santoro, Valeria, et al.
Publicado: (2020)

Flavin Adenine Dinucleotide Depletion Caused by electron transfer flavoprotein subunit alpha Haploinsufficiency Leads to Hepatic Steatosis and Injury in Zebrafish
por: Park, Ki‐Hoon, et al.
Publicado: (2021)

Nicotinamide adenine dinucleotide as a photocatalyst
por: Kim, Jinhyun, et al.
Publicado: (2019)

Nicotinamide Adenine Dinucleotide-Dependent Flavin Oxidoreductase of Mycoplasma hyopneumoniae Functions as a Potential Novel Virulence Factor and Not Only as a Metabolic Enzyme
por: Xie, Xing, et al.
Publicado: (2021)

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
por: Davila, Antonio, et al.
Publicado: (2018)

Driving the conversion of phytosterol to 9α-hydroxy-4-androstene-3,17-dione in Mycolicibacterium neoaurum by engineering the supply and regeneration of flavin adenine dinucleotide
por: Song, Lu, et al.
Publicado: (2023)

Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
por: Ernst, Insa M. A., et al.
Publicado: (2013)

Nicotinamide adenine dinucleotide suppresses epileptogenesis at an early stage
por: Liu, Juan, et al.
Publicado: (2017)

A Cas9 with PAM recognition for adenine dinucleotides
por: Chatterjee, Pranam, et al.
Publicado: (2020)

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors
por: She, Jing, et al.
Publicado: (2021)

Editorial: The Versatile Role of Nicotinamide Adenine Dinucleotide in Immunity
por: Rissiek, Björn, et al.
Publicado: (2021)

Functional and antigenic properties of GlpO from Mycoplasma mycoides subsp. mycoides SC: characterization of a flavin adenine dinucleotide-binding site deletion mutant
por: Bischof, Daniela F., et al.
Publicado: (2009)

Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
por: Huang, Fengming, et al.
Publicado: (2020)

Biocompatible MXene (Ti(3)C(2)T(x)) Immobilized with Flavin Adenine Dinucleotide as an Electrochemical Transducer for Hydrogen Peroxide Detection in Ovarian Cancer Cell Lines
por: Nagarajan, Ramila D., et al.
Publicado: (2021)

Photoinduced Electron Transfer from a 1,4,5,6-Tetrahydro Nicotinamide Adenine Dinucleotide (Phosphate) Analogue to Oxidized Flavin in an Ene-Reductase Flavoenzyme
por: Speirs, Magnus, et al.
Publicado: (2023)

The structural and functional roles of the flavin cofactor FAD in mammalian cryptochromes
por: Calloni, Giulia, et al.
Publicado: (2023)

Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD)
por: Yaku, Keisuke, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_of7m6d8jt2gejt54tcksq0loe4