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Viral Infection and Antiviral Treatments in Ocular Pathologies
Ocular viral infections are common and widespread globally. These infectious diseases are a major cause of acute red eyes and vision loss. The eye and its nearby tissues can be infected by several viral agents, causing infections with a short course and limited ocular implications or a long clinical...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694090/ https://www.ncbi.nlm.nih.gov/pubmed/36363815 http://dx.doi.org/10.3390/microorganisms10112224 |
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author | Petrillo, Francesco Petrillo, Arianna Sasso, Francesca Paola Schettino, Antonietta Maione, Angela Galdiero, Marilena |
author_facet | Petrillo, Francesco Petrillo, Arianna Sasso, Francesca Paola Schettino, Antonietta Maione, Angela Galdiero, Marilena |
author_sort | Petrillo, Francesco |
collection | PubMed |
description | Ocular viral infections are common and widespread globally. These infectious diseases are a major cause of acute red eyes and vision loss. The eye and its nearby tissues can be infected by several viral agents, causing infections with a short course and limited ocular implications or a long clinical progression and serious consequences for the function and structure of the ocular region. Several surveillance studies underline the increased emergence of drug resistance among pathogenic viral strains, limiting treatment options for these infections. Currently, in the event of resistant infections, topical or systemic corticosteroids are useful in the management of associated immune reactions in the eye, which contribute to ocular dysfunction. Many cases of viral eye infections are misdiagnosed as being of bacterial origin. In these cases, therapy begins late and is not targeted at the actual cause of the infection, often leading to severe ocular compromises, such as corneal infiltrates, conjunctival scarring, and reduced visual acuity. The present study aims at a better understanding of the viral pathogens that cause eye infections, along with the treatment options available. |
format | Online Article Text |
id | pubmed-9694090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96940902022-11-26 Viral Infection and Antiviral Treatments in Ocular Pathologies Petrillo, Francesco Petrillo, Arianna Sasso, Francesca Paola Schettino, Antonietta Maione, Angela Galdiero, Marilena Microorganisms Review Ocular viral infections are common and widespread globally. These infectious diseases are a major cause of acute red eyes and vision loss. The eye and its nearby tissues can be infected by several viral agents, causing infections with a short course and limited ocular implications or a long clinical progression and serious consequences for the function and structure of the ocular region. Several surveillance studies underline the increased emergence of drug resistance among pathogenic viral strains, limiting treatment options for these infections. Currently, in the event of resistant infections, topical or systemic corticosteroids are useful in the management of associated immune reactions in the eye, which contribute to ocular dysfunction. Many cases of viral eye infections are misdiagnosed as being of bacterial origin. In these cases, therapy begins late and is not targeted at the actual cause of the infection, often leading to severe ocular compromises, such as corneal infiltrates, conjunctival scarring, and reduced visual acuity. The present study aims at a better understanding of the viral pathogens that cause eye infections, along with the treatment options available. MDPI 2022-11-10 /pmc/articles/PMC9694090/ /pubmed/36363815 http://dx.doi.org/10.3390/microorganisms10112224 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Petrillo, Francesco Petrillo, Arianna Sasso, Francesca Paola Schettino, Antonietta Maione, Angela Galdiero, Marilena Viral Infection and Antiviral Treatments in Ocular Pathologies |
title | Viral Infection and Antiviral Treatments in Ocular Pathologies |
title_full | Viral Infection and Antiviral Treatments in Ocular Pathologies |
title_fullStr | Viral Infection and Antiviral Treatments in Ocular Pathologies |
title_full_unstemmed | Viral Infection and Antiviral Treatments in Ocular Pathologies |
title_short | Viral Infection and Antiviral Treatments in Ocular Pathologies |
title_sort | viral infection and antiviral treatments in ocular pathologies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694090/ https://www.ncbi.nlm.nih.gov/pubmed/36363815 http://dx.doi.org/10.3390/microorganisms10112224 |
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