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Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet

Pyruvate has two major fates upon entry into mitochondria, the oxidative decarboxylation to acetyl-CoA via the pyruvate decarboxylase complex or the biotin-dependent carboxylation to oxaloacetate via pyruvate carboxylase (Pcx). Here, we have generated mice with a liver-specific KO of pyruvate carbox...

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Detalles Bibliográficos
Autores principales:	Selen, Ebru S., Rodriguez, Susana, Cavagnini, Kyle S., Kim, Han-Byeol, Na, Chan Hyun, Wolfgang, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694104/ https://www.ncbi.nlm.nih.gov/pubmed/36441025 http://dx.doi.org/10.1016/j.jbc.2022.102648

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