Sequential hydrolysis of FAD by ecto-5′ nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B(2) into cells

Extracellular hydrolysis of flavin-adenine dinucleotide (FAD) and flavin mononucleotide (FMN) to riboflavin is thought to be important for cellular uptake of vitamin B(2) because FAD and FMN are hydrophilic and do not pass the plasma membrane. However, it is not clear whether FAD and FMN are hydroly...

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Detalles Bibliográficos
Autores principales: Shichinohe, Natsuki, Kobayashi, Daisuke, Izumi, Ayaka, Hatanaka, Kazuya, Fujita, Rio, Kinoshita, Taroh, Inoue, Norimitsu, Hamaue, Naoya, Wada, Keiji, Murakami, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694112/
https://www.ncbi.nlm.nih.gov/pubmed/36309091
http://dx.doi.org/10.1016/j.jbc.2022.102640

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