Design, Preparation, Characterization and Evaluation of Five Cocrystal Hydrates of Fluconazole with Hydroxybenzoic Acids

To modulate the physicochemical properties of fluconazole (FLZ), a multifunctional antifungal drug, the crystal engineering technique was employed. In this paper, five novel cocrystal hydrates of FLZ with a range of phenolic acids from the GRAS list, namely, 2,4-dihydroxybenzoic acid (24DHB), 3,4-di...

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Detalles Bibliográficos
Autores principales: Yu, Hongmei, Zhang, Baoxi, Liu, Meiju, Xing, Wenhui, Hu, Kun, Yang, Shiying, He, Guorong, Gong, Ningbo, Du, Guanhua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694130/
https://www.ncbi.nlm.nih.gov/pubmed/36432677
http://dx.doi.org/10.3390/pharmaceutics14112486

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