Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants

α-synuclein (αS) is the key component of synucleinopathies such as Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. αS was first linked to PD through the identification of point mutations in the SNCA gene, causing single amino acid substitutions within αS and familia...

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Detalles Bibliográficos
Autores principales: Watt, Kathryn J.C., Meade, Richard M., Williams, Robert J., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694135/
https://www.ncbi.nlm.nih.gov/pubmed/36208776
http://dx.doi.org/10.1016/j.jbc.2022.102565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694135/
https://www.ncbi.nlm.nih.gov/pubmed/36208776
http://dx.doi.org/10.1016/j.jbc.2022.102565

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