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Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants
α-synuclein (αS) is the key component of synucleinopathies such as Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy. αS was first linked to PD through the identification of point mutations in the SNCA gene, causing single amino acid substitutions within αS and familia...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694135/ https://www.ncbi.nlm.nih.gov/pubmed/36208776 http://dx.doi.org/10.1016/j.jbc.2022.102565 |