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Pharmaco-Toxicological Assessment of the Combined Cytotoxic Effects of Digoxin and Betulinic Acid in Melanoma Cells

Betulinic acid, a small molecule from pentacyclic triterpenes class, has been widely studied for its antitumor activity, revealing that it induces the apoptosis of tumor cells in a selective manner. In recent years, digoxin, a cardiac glycoside found particularly in the plant species Digitalis lanat...

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Detalles Bibliográficos
Autores principales: Rednic, Robert, Macasoi, Ioana, Pinzaru, Iulia, Dehelean, Cristina Adriana, Tomescu, Mirela-Cleopatra, Susan, Monica, Feier, Horea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694166/
https://www.ncbi.nlm.nih.gov/pubmed/36430989
http://dx.doi.org/10.3390/life12111855