SNH Amidation of 5-Nitroisoquinoline: Access to Nitro- and Nitroso Derivatives of Amides and Ureas on the Basis of Isoquinoline

For the first time, amides and ureas based on both 5-nitroisoquinoline and 5-nitrosoisoquinoline were obtained by direct nucleophilic substitution of hydrogen in the 5-nitroisoquinoline molecule. In the case of urea and monosubstituted ureas, only 5-nitrosoisoquinoline-6-amine is formed under anhydr...

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Detalles Bibliográficos
Autores principales: Avakyan, Elena K., Borovleva, Anastasia A., Pobedinskaya, Diana Yu., Demidov, Oleg P., Ermolenko, Artem P., Larin, Alexander N., Borovlev, Ivan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694180/
https://www.ncbi.nlm.nih.gov/pubmed/36431962
http://dx.doi.org/10.3390/molecules27227862

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