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The Anti-Tumor and Immunomodulatory Effects of PLGA-Based Docetaxel Nanoparticles in Lung Cancer: The Potential Involvement of Necroptotic Cell Death through Reactive Oxygen Species and Calcium Build-Up

Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to significant adverse effects and drug resistance. Nanotechnology may guide chemotherapeutic drugs directly and select...

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Detalles Bibliográficos
Autores principales: Gupta, Parul, Singh, Arpita, Verma, Ajay Kumar, Kant, Surya, Pandey, Anuj Kumar, Khare, Puneet, Prakash, Ved
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694303/
https://www.ncbi.nlm.nih.gov/pubmed/36366309
http://dx.doi.org/10.3390/vaccines10111801