Prospective Validation and Refinement of a Population Pharmacokinetic Model of Fludarabine in Children and Young Adults Undergoing Hematopoietic Cell Transplantation

Fludarabine is a nucleoside analog with antileukemic and immunosuppressive activity commonly used in allogeneic hematopoietic cell transplantation (HCT). Several fludarabine population pharmacokinetic (popPK) and pharmacodynamic models have been published enabling the movement towards precision dosi...

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Detalles Bibliográficos
Autores principales: Brooks, Jordan T., Solans, Belen P., Lu, Ying, Kharbanda, Sandhya, Dvorak, Christopher C., Lalefar, Nahal, Long, Susie, Gupta, Ashish O., Horn, Biljana, Lamba, Jatinder K., Huang, Liusheng, Apsel-Winger, Beth, Keizer, Ron J., Savic, Rada, Long-Boyle, Janel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694406/
https://www.ncbi.nlm.nih.gov/pubmed/36432661
http://dx.doi.org/10.3390/pharmaceutics14112462

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