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PIK3CAMutations in Breast Cancer Subtypes Other Than HR-Positive/HER2-Negative

The phosphoinositide 3-kinase (PI3K) pathway plays a key role in cancer, influencing growth, proliferation, and survival of tumor cells. PIK3CA mutations are generally oncogenic and responsible for uncontrolled cellular growth. PI3K inhibitors (PI3Ki) can inhibit the PI3K/AKT/mTOR pathway, although...

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Detalles Bibliográficos
Autores principales: Ascione, Liliana, Zagami, Paola, Nicolò, Eleonora, Crimini, Edoardo, Curigliano, Giuseppe, Criscitiello, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694420/
https://www.ncbi.nlm.nih.gov/pubmed/36579519
http://dx.doi.org/10.3390/jpm12111793