Cargando…
An open source plant kinase chemogenomics set
One hundred twenty‐nine protein kinases, selected to represent the diversity of the rice ( Oryza sativa ) kinome, were cloned and tested for expression in Escherichia coli . Forty of these rice kinases were purified and screened using differential scanning fluorimetry (DSF) against 627 diverse kinas...
Autores principales: | Ercoli, Maria Florencia, Ramos, Priscila Zonzini, Jain, Rashmi, Pilotte, Joseph, Dong, Oliver Xiaoou, Thompson, Ty, Wells, Carrow I., Elkins, Jonathan M., Edwards, Aled M., Couñago, Rafael M., Drewry, David H., Ronald, Pamela C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694430/ https://www.ncbi.nlm.nih.gov/pubmed/36447653 http://dx.doi.org/10.1002/pld3.460 |
Ejemplares similares
-
Progress towards a public chemogenomic set for protein kinases and a call for contributions
por: Drewry, David H., et al.
Publicado: (2017) -
Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors
por: Santiago, André da Silva, et al.
Publicado: (2018) -
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification
por: Wells, Carrow I., et al.
Publicado: (2021) -
Binding and structural analyses of potent inhibitors of the human Ca(2+)/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors
por: Profeta, Gerson S., et al.
Publicado: (2019) -
In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds
por: O’Byrne, Sean N., et al.
Publicado: (2020)