Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1

Formyl peptide receptors (FPRs) may contribute to inflammation in Alzheimer’s disease through interactions with neuropathological Amyloid beta (Aβ) peptides. Previous studies reported activation of FPR2 by Aβ(1-42), but further investigation of other FPRs and Aβ variants is needed. This study provid...

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Detalles Bibliográficos
Autores principales: Busch, Lukas, al Taleb, Zukaa, Tsai, Yu-Liang, Nguyen, Vu Thu Thuy, Lu, Qi, Synatschke, Christopher V., Endres, Kristina, Bufe, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694488/
https://www.ncbi.nlm.nih.gov/pubmed/36309087
http://dx.doi.org/10.1016/j.jbc.2022.102642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694488/
https://www.ncbi.nlm.nih.gov/pubmed/36309087
http://dx.doi.org/10.1016/j.jbc.2022.102642

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