Cargando…

Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1

Formyl peptide receptors (FPRs) may contribute to inflammation in Alzheimer’s disease through interactions with neuropathological Amyloid beta (Aβ) peptides. Previous studies reported activation of FPR2 by Aβ(1-42), but further investigation of other FPRs and Aβ variants is needed. This study provid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Busch, Lukas, al Taleb, Zukaa, Tsai, Yu-Liang, Nguyen, Vu Thu Thuy, Lu, Qi, Synatschke, Christopher V., Endres, Kristina, Bufe, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694488/ https://www.ncbi.nlm.nih.gov/pubmed/36309087 http://dx.doi.org/10.1016/j.jbc.2022.102642

Ejemplares similares

The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer’s Disease
por: Busch, Lukas, et al.
Publicado: (2022)

The tip of the iceberg? The underestimated potential of non-canonical beta-amyloids for Alzheimer’s disease
por: Busch, Lukas, et al.
Publicado: (2023)

A crate of Pandora: do amyloids from bacteria promote Alzheimer’s disease?
por: Nguyen, Vu Thu Thuy, et al.
Publicado: (2020)

Formyl Peptide Receptors from Immune and Vomeronasal System Exhibit Distinct Agonist Properties
por: Bufe, Bernd, et al.
Publicado: (2012)

In vitro Conversion of Vinyl to Formyl Groups in Naturally Occurring Chlorophylls
por: Loughlin, Patrick C., et al.
Publicado: (2014)

Detection of Nα-terminally formylated native proteins by a pan-N-formyl methionine-specific antibody
por: Kim, Dasom, et al.
Publicado: (2023)

Role of N-terminal protein formylation in central metabolic processes in Staphylococcus aureus
por: Mader, Diana, et al.
Publicado: (2013)

Impact of Gut Microbiome Manipulation in 5xFAD Mice on Alzheimer’s Disease-Like Pathology
por: Guilherme, Malena dos Santos, et al.
Publicado: (2021)

Influence of Acetylcholine Esterase Inhibitors and Memantine, Clinically Approved for Alzheimer’s Dementia Treatment, on Intestinal Properties of the Mouse
por: Nguyen, Vu Thu Thuy, et al.
Publicado: (2021)

Formylation of Amines
por: Gerack, Ciera J., et al.
Publicado: (2014)

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells
por: Slowik, Alexander, et al.
Publicado: (2012)

Differential activation of polymorphisms of the formyl peptide receptor by formyl peptides
por: Mills, John S.
Publicado: (2007)

Emergence of Alternative Structures in Amyloid Beta 1-42 Monomeric Landscape by N-terminal Hexapeptide Amyloid Inhibitors
por: Chakraborty, Srirupa, et al.
Publicado: (2017)

Comparative Nucleosomal Reactivity of 5‐Formyl‐Uridine and 5‐Formyl‐Cytidine
por: Runtsch, Leander Simon, et al.
Publicado: (2021)

An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect
por: Liu, Yu-Hui, et al.
Publicado: (2015)

Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction
por: Lin, Edward Y. S., et al.
Publicado: (2018)

Using Drosophila to identify naturally occurring genetic modifiers of amyloid beta 42- and tau-induced toxicity
por: Yang, Ming, et al.
Publicado: (2023)

N-Formyl-L-aspartate mediates chemotaxis in sperm via the beta-2-adrenergic receptor
por: Panchal, Durva, et al.
Publicado: (2022)

Starting with a degron: N-terminal formyl-methionine of nascent bacterial proteins contributes to their proteolytic control
por: Dohmen, R. Jürgen
Publicado: (2015)

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
por: Davis, Richard C, et al.
Publicado: (2011)

Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer’s disease
por: Du, Hongtao, et al.
Publicado: (2023)

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins
por: Piatkov, Konstantin I., et al.
Publicado: (2015)

Voluntary Wheel Running Did Not Alter Gene Expression in 5xfad Mice, but in Wild-Type Animals Exclusively after One-Day of Physical Activity
por: Wierczeiko, Anna, et al.
Publicado: (2021)

Acute-serum amyloid A and A-SAA-derived peptides as formyl peptide receptor (FPR) 2 ligands
por: Abouelasrar Salama, Sara, et al.
Publicado: (2023)

Cell-Instructive Surface Gradients of Photoresponsive Amyloid-like Fibrils
por: Ender, Adriana Maria, et al.
Publicado: (2021)

Preferential binding of fullerene and fullerenol with the N-terminal and middle regions of amyloid beta peptide: an in silico investigation
por: Pandya, Vishal, et al.
Publicado: (2018)

Amyloid-beta and Alzheimer’s disease: the role of neprilysin-2 in amyloid-beta clearance
por: Marr, Robert A., et al.
Publicado: (2014)

The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer’s Disease
por: Trojan, Ewa, et al.
Publicado: (2021)

Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1
por: Liu, Fu-Chao, et al.
Publicado: (2017)

N(6) -Methyladenosine Modification in Chronic Stress Response Due to Social Hierarchy Positioning of Mice
por: dos Santos Guilherme, Malena, et al.
Publicado: (2021)

N(ε)-Formylation of lysine is a widespread post-translational modification of nuclear proteins occurring at residues involved in regulation of chromatin function
por: Wiśniewski, Jacek R., et al.
Publicado: (2008)

Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2
por: al Taleb, Zukaa, et al.
Publicado: (2016)

The novel amyloid-beta peptide aptamer inhibits intracellular amyloid-beta peptide toxicity
por: Wang, Xu, et al.
Publicado: (2013)

Amyloid-beta Alzheimer targets — protein processing, lipid rafts, and amyloid-beta pores
por: Arbor, Sage C., et al.
Publicado: (2016)

Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils
por: Choi, Erika Y., et al.
Publicado: (2020)

Amyloid-Beta Interaction with Mitochondria
por: Pagani, Lucia, et al.
Publicado: (2011)

Beta-amyloid imaging with florbetaben
por: Sabri, Osama, et al.
Publicado: (2015)

Beta-amyloid imaging in dementia
por: Chun, Kyung Ah
Publicado: (2018)

Copper-catalyzed formylation of alkenyl C–H bonds using BrCHCl(2) as a stoichiometric formylating reagent
por: Bao, Yan, et al.
Publicado: (2018)

Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC
por: Javed, Ibrahim, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p8ck8e87v2c2glao5ulqpokos5