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Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study

BACKGROUND: Concurrent opioid and stimulant use is on the rise in North America. This increasing trend of use has been observed in the general population, and among people released from prison in British Columbia (BC), who face an elevated risk of overdose post-release. Opioid agonist treatment is a...

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Autores principales: Palis, Heather, Zhao, Bin, Young, Pam, Korchinski, Mo, Greiner, Leigh, Nicholls, Tonia, Slaunwhite, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694574/
https://www.ncbi.nlm.nih.gov/pubmed/36434706
http://dx.doi.org/10.1186/s13011-022-00504-z
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author Palis, Heather
Zhao, Bin
Young, Pam
Korchinski, Mo
Greiner, Leigh
Nicholls, Tonia
Slaunwhite, Amanda
author_facet Palis, Heather
Zhao, Bin
Young, Pam
Korchinski, Mo
Greiner, Leigh
Nicholls, Tonia
Slaunwhite, Amanda
author_sort Palis, Heather
collection PubMed
description BACKGROUND: Concurrent opioid and stimulant use is on the rise in North America. This increasing trend of use has been observed in the general population, and among people released from prison in British Columbia (BC), who face an elevated risk of overdose post-release. Opioid agonist treatment is an effective treatment for opioid use disorder and reduces risk of overdose mortality. In the context of rising concurrent stimulant use among people with opioid use disorder, this study aims to investigate the impact of stimulant use disorder on opioid agonist treatment dispensation following release from prison in BC. METHODS: Linked health and corrections records were retrieved for releases between January 1(st) 2015 and December 29(th) 2018 (N = 13,380). Hospital and primary-care administrative health records were used to identify opioid and stimulant use disorder and mental illness. Age, sex, and health region were derived from BC’s Client Roster. Incarceration data were retrieved from provincial prison records. Opioid agonist treatment data was retrieved from BC’s provincial drug dispensation database. A generalized estimating equation produced estimates for the relationship of stimulant use disorder and opioid agonist treatment dispensation within two days post-release. RESULTS: Cases of release among people with an opioid use disorder were identified (N = 13,380). Approximately 25% (N = 3,328) of releases ended in opioid agonist treatment dispensation within two days post-release. A statistically significant interaction of stimulant use disorder and mental illness was identified. Stratified odds ratios (ORs) found that in the presence of mental illness, stimulant use disorder was associated with lower odds of obtaining OAT [(OR) = 0.73, 95% confidence interval (CI) = 0.64–0.84)] while in the absence of mental illness, this relationship did not hold [OR = 0.89, 95% CI = 0.70–1.13]. CONCLUSIONS: People with mental illness and stimulant use disorder diagnoses have a lower odds of being dispensed agonist treatment post-release compared to people with mental illness alone. There is a critical need to scale up and adapt opioid agonist treatment and ancillary harm reduction, and treatment services to reach people released from prison who have concurrent stimulant use disorder and mental illness diagnoses. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13011-022-00504-z.
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spelling pubmed-96945742022-11-26 Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study Palis, Heather Zhao, Bin Young, Pam Korchinski, Mo Greiner, Leigh Nicholls, Tonia Slaunwhite, Amanda Subst Abuse Treat Prev Policy Research BACKGROUND: Concurrent opioid and stimulant use is on the rise in North America. This increasing trend of use has been observed in the general population, and among people released from prison in British Columbia (BC), who face an elevated risk of overdose post-release. Opioid agonist treatment is an effective treatment for opioid use disorder and reduces risk of overdose mortality. In the context of rising concurrent stimulant use among people with opioid use disorder, this study aims to investigate the impact of stimulant use disorder on opioid agonist treatment dispensation following release from prison in BC. METHODS: Linked health and corrections records were retrieved for releases between January 1(st) 2015 and December 29(th) 2018 (N = 13,380). Hospital and primary-care administrative health records were used to identify opioid and stimulant use disorder and mental illness. Age, sex, and health region were derived from BC’s Client Roster. Incarceration data were retrieved from provincial prison records. Opioid agonist treatment data was retrieved from BC’s provincial drug dispensation database. A generalized estimating equation produced estimates for the relationship of stimulant use disorder and opioid agonist treatment dispensation within two days post-release. RESULTS: Cases of release among people with an opioid use disorder were identified (N = 13,380). Approximately 25% (N = 3,328) of releases ended in opioid agonist treatment dispensation within two days post-release. A statistically significant interaction of stimulant use disorder and mental illness was identified. Stratified odds ratios (ORs) found that in the presence of mental illness, stimulant use disorder was associated with lower odds of obtaining OAT [(OR) = 0.73, 95% confidence interval (CI) = 0.64–0.84)] while in the absence of mental illness, this relationship did not hold [OR = 0.89, 95% CI = 0.70–1.13]. CONCLUSIONS: People with mental illness and stimulant use disorder diagnoses have a lower odds of being dispensed agonist treatment post-release compared to people with mental illness alone. There is a critical need to scale up and adapt opioid agonist treatment and ancillary harm reduction, and treatment services to reach people released from prison who have concurrent stimulant use disorder and mental illness diagnoses. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13011-022-00504-z. BioMed Central 2022-11-24 /pmc/articles/PMC9694574/ /pubmed/36434706 http://dx.doi.org/10.1186/s13011-022-00504-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Palis, Heather
Zhao, Bin
Young, Pam
Korchinski, Mo
Greiner, Leigh
Nicholls, Tonia
Slaunwhite, Amanda
Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title_full Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title_fullStr Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title_full_unstemmed Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title_short Stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
title_sort stimulant use disorder diagnosis and opioid agonist treatment dispensation following release from prison: a cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694574/
https://www.ncbi.nlm.nih.gov/pubmed/36434706
http://dx.doi.org/10.1186/s13011-022-00504-z
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