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Molecular Mechanisms for Ketone Body Metabolism, Signaling Functions, and Therapeutic Potential in Cancer

The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic ketogenesis are catabolized to acetyl-CoA through ketolysis in extrahepatic tissues, followed by the tricarboxylic acid cycle and el...

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Detalles Bibliográficos
Autores principales: Hwang, Chi Yeon, Choe, Wonchae, Yoon, Kyung-Sik, Ha, Joohun, Kim, Sung Soo, Yeo, Eui-Ju, Kang, Insug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694619/
https://www.ncbi.nlm.nih.gov/pubmed/36432618
http://dx.doi.org/10.3390/nu14224932

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