3K3A-Activated Protein C Prevents Microglia Activation, Inhibits NLRP3 Inflammasome and Limits Ocular Inflammation

3K3A-Activated Protein C (APC) is a recombinant variant of the physiological anticoagulant APC with pleiotropic cytoprotective properties albeit without the bleeding risks. The anti-inflammatory activities of 3K3A-APC were demonstrated in multiple preclinical injury models, including various neurolo...

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Detalles Bibliográficos
Autores principales: Palevski, Dahlia, Ben-David, Gil, Weinberger, Yehonatan, Haj Daood, Rabeei, Fernández, José A., Budnik, Ivan, Levy-Mendelovich, Sarina, Kenet, Gili, Nisgav, Yael, Weinberger, Dov, Griffin, John H., Livnat, Tami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694680/
https://www.ncbi.nlm.nih.gov/pubmed/36430674
http://dx.doi.org/10.3390/ijms232214196

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