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dNAGLU Extends Life Span and Promotes Fitness and Stress Resistance in Drosophila

To identify new factors that promote longevity and healthy aging, we studied Drosophila CG13397, an ortholog of the human NAGLU gene, a lysosomal enzyme overexpressed in centenarians. We found that the overexpression of CG13397 (dNAGLU) ubiquitously, or tissue specifically, in the nervous system or...

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Detalles Bibliográficos
Autores principales:	Xue, Rubing, Yang, Ke, Xiao, Fuhui, Yang, Liping, Chen, Guijun, Li, Yongxuan, Ye, Yunshuang, Chen, Kangning, Smith, Sheryl T., Li, Gonghua, Kong, Qingpeng, Zhou, Jumin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694703/ https://www.ncbi.nlm.nih.gov/pubmed/36430913 http://dx.doi.org/10.3390/ijms232214433

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