Limitations of Tamoxifen Application for In Vivo Genome Editing Using Cre/ER(T2) System

Inducible Cre-dependent systems are frequently used to produce both conditional knockouts and transgenic mice with regulated expression of the gene of interest. Induction can be achieved by doxycycline-dependent transcription of the wild type gene or OH-tamoxifen-dependent nuclear translocation of t...

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Detalles Bibliográficos
Autores principales: Ilchuk, Leonid A., Stavskaya, Nina I., Varlamova, Ekaterina A., Khamidullina, Alvina I., Tatarskiy, Victor V., Mogila, Vladislav A., Kolbutova, Ksenia B., Bogdan, Sergey A., Sheremetov, Alexey M., Baulin, Alexandr N., Filatova, Irina A., Silaeva, Yulia Yu., Filatov, Maxim A., Bruter, Alexandra V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694728/
https://www.ncbi.nlm.nih.gov/pubmed/36430553
http://dx.doi.org/10.3390/ijms232214077

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