The Role of Arrestin-1 Middle Loop in Rhodopsin Binding

Arrestins preferentially bind active phosphorylated G protein-coupled receptors (GPCRs). The middle loop, highly conserved in all arrestin subtypes, is localized in the central crest on the GPCR-binding side. Upon receptor binding, it directly interacts with bound GPCR and demonstrates the largest m...

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Detalles Bibliográficos
Autores principales: Vishnivetskiy, Sergey A., Huh, Elizabeth K., Karnam, Preethi C., Oviedo, Samantha, Gurevich, Eugenia V., Gurevich, Vsevolod V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694801/
https://www.ncbi.nlm.nih.gov/pubmed/36430370
http://dx.doi.org/10.3390/ijms232213887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694801/
https://www.ncbi.nlm.nih.gov/pubmed/36430370
http://dx.doi.org/10.3390/ijms232213887

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