Cargando…

Rapid Whole Genome Sequencing in Critically Ill Neonates Enables Precision Medicine Pipeline

Rapid genome sequencing in critically ill infants is increasingly identified as a crucial test for providing targeted and informed patient care. We report the outcomes of a pilot study wherein eight critically ill neonates received rapid whole genome sequencing with parental samples in an effort to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beaman, Makenzie, Fisher, Kimberley, McDonald, Marie, Tan, Queenie K. G., Jackson, David, Cocanougher, Benjamin T., Landstrom, Andrew P., Hobbs, Charlotte A., Cotten, Michael, Cohen, Jennifer L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694815/ https://www.ncbi.nlm.nih.gov/pubmed/36422100 http://dx.doi.org/10.3390/jpm12111924

Ejemplares similares

Optimizing a Whole-Genome Sequencing Data Processing Pipeline for Precision Surveillance of Health Care-Associated Infections
por: Huang, Weihua, et al.
Publicado: (2019)

The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification
por: Buswinka, Christopher J., et al.
Publicado: (2023)

A Pilot Phase I Trial of Allogeneic Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells in Neonates With Hypoxic-Ischemic Encephalopathy
por: Cotten, Charles Michael, et al.
Publicado: (2023)

From Forensics to Clinical Research: Expanding the Variant Calling Pipeline for the Precision ID mtDNA Whole Genome Panel
por: Cortes-Figueiredo, Filipe, et al.
Publicado: (2021)

Precise Identification of Recurrent Somatic Mutations in Oral Cancer Through Whole-Exome Sequencing Using Multiple Mutation Calling Pipelines
por: Lin, Li-Han, et al.
Publicado: (2021)

NeoRS: A Neonatal Resting State fMRI Data Preprocessing Pipeline
por: Enguix, Vicente, et al.
Publicado: (2022)

mRNA vaccine development for cholangiocarcinoma: a precise pipeline
por: Tang, Tian-Yu, et al.
Publicado: (2022)

Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices
por: Chen, Wei, et al.
Publicado: (2023)

Enabling Genomics Pipelines in Commodity Personal Computers With Flash Storage
por: Cadenelli, Nicola, et al.
Publicado: (2021)

SPARC enables genetic manipulation of precise proportions of cells.
por: Isaacman-Beck, Jesse, et al.
Publicado: (2020)

Agile application security: enabling security in a continuous delivery pipeline
por: Bell, Laura, et al.
Publicado: (2016)

SIMPLEX: Cloud-Enabled Pipeline for the Comprehensive Analysis of Exome Sequencing Data
por: Fischer, Maria, et al.
Publicado: (2012)

Computer vision and machine learning enabled soybean root phenotyping pipeline
por: Falk, Kevin G., et al.
Publicado: (2020)

Robots, pipelines, polyproteins: Enabling multiprotein expression in prokaryotic and eukaryotic cells
por: Vijayachandran, Lakshmi Sumitra, et al.
Publicado: (2011)

MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms
por: Erdem, Cemal, et al.
Publicado: (2023)

Location, location, location: utilizing pipelines and services to more effectively georeference the world's biodiversity data
por: Hill, Andrew W, et al.
Publicado: (2009)

Multiple Variant Calling Pipelines in Wheat Whole Exome Sequencing
por: Cagirici, H. Busra, et al.
Publicado: (2021)

Impact of concurrency on the performance of a whole exome sequencing pipeline
por: Dall’Olio, Daniele, et al.
Publicado: (2021)

SanPy: A whole-cell electrophysiology analysis pipeline
por: Guarina, Laura, et al.
Publicado: (2023)

Organoids as an Enabler of Precision Immuno-Oncology
por: Zhao, Junzhe, et al.
Publicado: (2023)

Mortality in a neonate with molybdenum cofactor deficiency illustrates the need for a comprehensive rapid precision medicine system
por: Kingsmore, Stephen F., et al.
Publicado: (2020)

Precision Medicine for Neonatal Sepsis
por: Ng, Sherrianne, et al.
Publicado: (2018)

Editorial: Precision Medicine in Neonates
por: Allegaert, Karel, et al.
Publicado: (2021)

appreci8: a pipeline for precise variant calling integrating 8 tools
por: Sandmann, Sarah, et al.
Publicado: (2018)

Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer
por: Altunel, Erdem, et al.
Publicado: (2020)

A multiplexed, automated evolution pipeline enables scalable discovery and characterization of biosensors
por: Townshend, Brent, et al.
Publicado: (2021)

Neural simulation pipeline: Enabling container-based simulations on-premise and in public clouds
por: Chlasta, Karol, et al.
Publicado: (2023)

Feasibility of Embedding a Scalable, Virtually Enabled Biorepository in the Electronic Health Record for Precision Medicine
por: DeMerle, Kimberley M., et al.
Publicado: (2021)

An integrated computational pipeline and database to support whole-genome sequence annotation
por: Mungall, CJ, et al.
Publicado: (2002)

WEP: a high-performance analysis pipeline for whole-exome data
por: D'Antonio, Mattia, et al.
Publicado: (2013)

Automated contouring and planning pipeline for hippocampal-avoidant whole-brain radiotherapy
por: Feng, Christine H., et al.
Publicado: (2020)

Candida auris Whole-Genome Sequence Benchmark Dataset for Phylogenomic Pipelines
por: Welsh, Rory M., et al.
Publicado: (2021)

Correction to: Impact of concurrency on the performance of a whole exome sequencing pipeline
por: Dall’Olio, Daniele, et al.
Publicado: (2021)

An optimized pipeline for live imaging whole Arabidopsis leaves at cellular resolution
por: Harline, Kate, et al.
Publicado: (2023)

From Wet‐Lab to Variations: Concordance and Speed of Bioinformatics Pipelines for Whole Genome and Whole Exome Sequencing
por: Laurie, Steve, et al.
Publicado: (2016)

The ‘Digital Twin’ to enable the vision of precision cardiology
por: Corral-Acero, Jorge, et al.
Publicado: (2020)

Noncoding RNome as Enabling Biomarkers for Precision Health
por: Cheong, Jit Kong, et al.
Publicado: (2022)

Critical Illness Polyneuropathy in Patients With Major Burn Injuries
por: Chan, Queenie, et al.
Publicado: (2010)

A memory-driven auditory program ensures selective and precise vocal imitation in zebra finches
por: Liu, Wan-chun, et al.
Publicado: (2021)

A midas plugin to enable construction of reproducible web-based image processing pipelines
por: Grauer, Michael, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3rsjturu6phbjv90c8ukcocqc1