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Learning from TCR Signaling and Immunological Synapse Assembly to Build New Chimeric Antigen Receptors (CARs)

Chimeric antigen receptor (CAR) T cell immunotherapy is a revolutionary pillar in cancer treatment. Clinical experience has shown remarkable successes in the treatment of certain hematological malignancies but only limited efficacy against B cell chronic lymphocytic leukemia (CLL) and other cancer t...

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Detalles Bibliográficos
Autores principales: Cassioli, Chiara, Patrussi, Laura, Valitutti, Salvatore, Baldari, Cosima T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694822/
https://www.ncbi.nlm.nih.gov/pubmed/36430728
http://dx.doi.org/10.3390/ijms232214255

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