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Glycyrrhizin Interacts with TLR4 and TLR9 to Resolve P. aeruginosa Keratitis

This study tests the mechanism(s) of glycyrrhizin (GLY) protection against P. aeruginosa keratitis. Female C57BL/6 (B6), TLR4 knockout (TLR4KO), myeloid specific TLR4KO (mTLR4KO), their wildtype (WT) littermates, and TLR9 knockout (TLR9KO) mice were infected with P. aeruginosa KEI 1025 and treated w...

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Detalles Bibliográficos
Autores principales: Somayajulu, Mallika, McClellan, Sharon A., Farooq, Shukkur Muhammed, Pitchaikannu, Ahalya, Xu, Shunbin, Hazlett, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694947/
https://www.ncbi.nlm.nih.gov/pubmed/36422579
http://dx.doi.org/10.3390/pathogens11111327