Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA

The interferon-induced myxovirus resistance protein A (MxA) is a potent restriction factor that prevents zoonotic infection from influenza A virus (IAV) subtype H7N9. Individuals expressing antivirally inactive MxA variants are highly susceptible to these infections. However, human-adapted IAVs have...

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Detalles Bibliográficos
Autores principales: Petric, Philipp P., King, Jacqueline, Graf, Laura, Pohlmann, Anne, Beer, Martin, Schwemmle, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695009/
https://www.ncbi.nlm.nih.gov/pubmed/36366429
http://dx.doi.org/10.3390/v14112331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695009/
https://www.ncbi.nlm.nih.gov/pubmed/36366429
http://dx.doi.org/10.3390/v14112331

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