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Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA

The interferon-induced myxovirus resistance protein A (MxA) is a potent restriction factor that prevents zoonotic infection from influenza A virus (IAV) subtype H7N9. Individuals expressing antivirally inactive MxA variants are highly susceptible to these infections. However, human-adapted IAVs have...

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Detalles Bibliográficos
Autores principales:	Petric, Philipp P., King, Jacqueline, Graf, Laura, Pohlmann, Anne, Beer, Martin, Schwemmle, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695009/ https://www.ncbi.nlm.nih.gov/pubmed/36366429 http://dx.doi.org/10.3390/v14112331

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