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Comparative Studies of Palmatine with Metformin and Glimepiride on the Modulation of Insulin Dependent Signaling Pathway In Vitro, In Vivo & Ex Vivo
(1) Insulin resistance, a symptom of type 2 diabetes mellitus (T2DM), is caused by the inactivation of the insulin signaling pathway, which includes IRS-PI3K-IRS-1-PKC-AKT2 and GLUT4. Metformin (biguanide) and glimepiride (sulfonylurea) are both drugs that are derivatives of urea, and they are widel...
Autores principales: | Nwabueze, Okechukwu Patrick, Sharma, Mridula, Balachandran, Abbirami, Gaurav, Anand, Abdul Rani, Anis Najwa, Małgorzata, Jeleń, Beata, Morak-Młodawska, Lavilla, Charlie A., Billacura, Merell P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695187/ https://www.ncbi.nlm.nih.gov/pubmed/36355489 http://dx.doi.org/10.3390/ph15111317 |
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