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Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis

Several biologic therapies have been developed to treat moderate-to-severe psoriasis, with patients exhibiting different clinical benefits, possibly due to the heterogeneity of pathogenic processes underlying their conditions. Ustekinumab targets the IL-12/IL-23-p40 subunit and inhibits type-1 and t...

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Detalles Bibliográficos
Autores principales: Morelli, Martina, Galluzzo, Marco, Scarponi, Claudia, Madonna, Stefania, Scaglione, Giovanni Luca, Girolomoni, Giampiero, Talamonti, Marina, Bianchi, Luca, Albanesi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695538/
https://www.ncbi.nlm.nih.gov/pubmed/36423071
http://dx.doi.org/10.3390/vaccines10111977