Antisense Oligonucleotide Therapy for the Nervous System: From Bench to Bedside with Emphasis on Pediatric Neurology

Antisense oligonucleotides (ASOs) are disease-modifying agents affecting protein-coding and noncoding ribonucleic acids. Depending on the chemical modification and the location of hybridization, ASOs are able to reduce the level of toxic proteins, increase the level of functional protein, or modify...

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Detalles Bibliográficos
Autores principales: Amanat, Man, Nemeth, Christina L., Fine, Amena Smith, Leung, Doris G., Fatemi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695718/
https://www.ncbi.nlm.nih.gov/pubmed/36365206
http://dx.doi.org/10.3390/pharmaceutics14112389

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