Cargando…

Synthesis and Biological Evaluation of Novel Pyrimidine Amine Derivatives Bearing Bicyclic Monoterpene Moieties

A series of novel pinanyl pyrimidine amine derivatives (1e~1n) and camphoryl pyrimidine amine derivatives (2b~2f) bearing bicyclic monoterpene moieties were designed and synthesized from natural and renewable nopinone and camphor. All chemical structures of target compounds were characterized by (1)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Mingguang, Wang, Yunyun, Wang, Shifa, Wu, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695817/ https://www.ncbi.nlm.nih.gov/pubmed/36432205 http://dx.doi.org/10.3390/molecules27228104

Ejemplares similares

Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety
por: Lan, Wenjun, et al.
Publicado: (2022)

Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors
por: Halawa, Ahmed H., et al.
Publicado: (2019)

Anaerobic Degradation of Bicyclic Monoterpenes in Castellaniella defragrans
por: Puentes-Cala, Edinson, et al.
Publicado: (2018)

Synthesis and Biological Evaluation of Norcantharidin Derivatives Possessing an Aromatic Amine Moiety as Antifungal Agents
por: Wang, Yang, et al.
Publicado: (2015)

Synthesis and Antifungal Activity of Pyrimidine Derivatives Containing an Amide Moiety
por: Wu, Wenneng, et al.
Publicado: (2021)

Design, Synthesis, and Biological Evaluation of Novel Benzofuran Derivatives Bearing N-Aryl Piperazine Moiety
por: Ma, Yulu, et al.
Publicado: (2016)

Synthesis, Antifungal, and Antibacterial Activities of Novel Benzoylurea Derivatives Containing a Pyrimidine Moiety
por: An, Jiansong, et al.
Publicado: (2023)

Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
por: Mahal, Ahmed, et al.
Publicado: (2017)

Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues
por: Andreeva, Olga V., et al.
Publicado: (2021)

Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety
por: Sadeghian-Rizi, Sedighe, et al.
Publicado: (2018)

Synthesis of Some Benzofuran Derivatives Containing Pyrimidine Moiety as Potent Antimicrobial Agents
por: Venkatesh, Talavara, et al.
Publicado: (2018)

Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety
por: Ghorab, Mostafa M., et al.
Publicado: (2017)

Design, Synthesis and Bioactivity of Novel Pyrimidine Sulfonate Esters Containing Thioether Moiety
por: Li, Changkun, et al.
Publicado: (2023)

Synthesis of eunicellane-type bicycles embedding a 1,3-cyclohexadiene moiety
por: Frichert, Alex, et al.
Publicado: (2018)

Synthesis and Biological Evaluation of Dipeptide-Based Stilbene Derivatives Bearing a Biheterocyclic Moiety as Potential Fungicides
por: Zhu, Yongchuang, et al.
Publicado: (2022)

Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
por: Noguchi, Yoshihiko, et al.
Publicado: (2016)

Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity
por: Sedenkova, Kseniya N., et al.
Publicado: (2022)

Novel 5′-Norcarbocyclic Derivatives of Bicyclic Pyrrolo- and Furano[2,3-d]Pyrimidine Nucleosides
por: Klimenko, Anna A., et al.
Publicado: (2018)

Novel camphor-based pyrimidine derivatives induced cancer cell death through a ROS-mediated mitochondrial apoptosis pathway
por: Zhang, Yan, et al.
Publicado: (2019)

Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments
por: Munkuev, Aldar A., et al.
Publicado: (2021)

Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties
por: Ivankin, Dmitry I., et al.
Publicado: (2023)

Chemical Synthesis and Biological Activities of Novel Pleuromutilin Derivatives with Substituted Amino Moiety
por: Shang, Ruofeng, et al.
Publicado: (2013)

Synthesis and Antiproliferative Evaluation of Novel Longifolene-Derived Tetralone Derivatives Bearing 1,2,4-Triazole Moiety
por: Zhu, Xia-Ping, et al.
Publicado: (2020)

Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-Toxoplasma gondii agents
por: Luan, Tian, et al.
Publicado: (2019)

Synthesis, Characterization, and Anti-Inflammatory Activities of Methyl Salicylate Derivatives Bearing Piperazine Moiety
por: Li, Jingfen, et al.
Publicado: (2016)

Borneol, a Bicyclic Monoterpene Alcohol, Reduces Nociceptive Behavior and Inflammatory Response in Mice
por: Almeida, Jackson Roberto Guedes da Silva, et al.
Publicado: (2013)

Synthesis and Anticancer Evaluation of New Thiazole and Thiadiazole Derivatives Bearing Acetanilide Moiety
por: El-Rayyes, Ali, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of N- Pyrazolyl Derivatives and Pyrazolopyrimidine Bearing a Biologically Active Sulfonamide Moiety as Potential Antimicrobial Agent
por: Hafez, Hend N., et al.
Publicado: (2016)

Synthesis and Antimicrobial Evaluation of Some Novel Thiazole, Pyridone, Pyrazole, Chromene, Hydrazone Derivatives Bearing a Biologically Active Sulfonamide Moiety
por: Darwish, Elham S., et al.
Publicado: (2014)

Synthesis and antimicrobial activity of some novel 1,2-dihydro-[1,2,4]triazolo[1,5-a]pyrimidines bearing amino acid moiety
por: Mohamed, Mounir A. A., et al.
Publicado: (2021)

Synthesis, biological evaluation and molecular docking investigation of new sulphonamide derivatives bearing naphthalene moiety as potent tubulin polymerisation inhibitors
por: Wang, Guangcheng, et al.
Publicado: (2021)

Design, synthesis, computational study and cytotoxic evaluation of some new quinazoline derivatives containing pyrimidine moiety
por: Zare, Somayeh, et al.
Publicado: (2023)

Radical and Cationic Pathways in C(sp(3))–H Bond Oxygenation by Dioxiranes of Bicyclic and Spirocyclic Hydrocarbons Bearing Cyclopropane Moieties
por: Galeotti, Marco, et al.
Publicado: (2023)

Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer’s agents
por: Zondagh, Luke S., et al.
Publicado: (2020)

Synthesis and biological activities of novel trifluoromethylpyridine amide derivatives containing sulfur moieties
por: Guo, S. X., et al.
Publicado: (2020)

New Monoterpene Glycoside Paeoniflorin Derivatives as NO and IL-1β Inhibitors: Synthesis and Biological Evaluation
por: Chen, Yongjie, et al.
Publicado: (2023)

Biological evaluation, docking and molecular dynamic simulation of some novel diaryl urea derivatives bearing quinoxalindione moiety
por: Sadeghian-Rizi, Sedighe, et al.
Publicado: (2017)

Coumarin derivatives bearing benzoheterocycle moiety: synthesis, cholinesterase inhibitory, and docking simulation study
por: Hirbod, Kimia, et al.
Publicado: (2017)

Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors
por: Tu, Yuanbiao, et al.
Publicado: (2018)

Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties
por: Litim, Bilal, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ei036sekl2hlsofu5pgrl2nvcf