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The Farnesoid X Receptor as a Master Regulator of Hepatotoxicity

The nuclear receptor farnesoid X receptor (FXR, NR1H4) is a bile acid (BA) sensor that links the enterohepatic circuit that regulates BA metabolism and elimination to systemic lipid homeostasis. Furthermore, FXR represents a real guardian of the hepatic function, preserving, in a multifactorial fash...

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Detalles Bibliográficos
Autores principales:	Rausch, Magdalena, Samodelov, Sophia L., Visentin, Michele, Kullak-Ublick, Gerd A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695947/ https://www.ncbi.nlm.nih.gov/pubmed/36430444 http://dx.doi.org/10.3390/ijms232213967

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