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Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer
Background and Objective: Blood loss represents a long-standing concern of radical prostatectomy (RP). This study aimed to assess how red line cell values changed following robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Materials and Methods: The blood panels of 453 consecuti...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695953/ https://www.ncbi.nlm.nih.gov/pubmed/36363477 http://dx.doi.org/10.3390/medicina58111520 |
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author | Di Bello, Francesco Di Mauro, Ernesto Collà Ruvolo, Claudia Creta, Massimiliano La Rocca, Roberto Celentano, Giuseppe Capece, Marco Napolitano, Luigi Morra, Simone Pezone, Gabriele Passaro, Francesco De Luca, Ciro Mangiapia, Francesco Logrieco, Nicola Buonanno, Pasquale Servillo, Giuseppe Imbimbo, Ciro Mirone, Vincenzo Longo, Nicola Califano, Gianluigi |
author_facet | Di Bello, Francesco Di Mauro, Ernesto Collà Ruvolo, Claudia Creta, Massimiliano La Rocca, Roberto Celentano, Giuseppe Capece, Marco Napolitano, Luigi Morra, Simone Pezone, Gabriele Passaro, Francesco De Luca, Ciro Mangiapia, Francesco Logrieco, Nicola Buonanno, Pasquale Servillo, Giuseppe Imbimbo, Ciro Mirone, Vincenzo Longo, Nicola Califano, Gianluigi |
author_sort | Di Bello, Francesco |
collection | PubMed |
description | Background and Objective: Blood loss represents a long-standing concern of radical prostatectomy (RP). This study aimed to assess how red line cell values changed following robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Materials and Methods: The blood panels of 453 consecutive PCa patients undergoing RARP at a single tertiary academic referral center, from September 2020 to April 2022, were reviewed. Data from 363 patients with the blood panel available for the following timeframe: within seven days before surgery, six hours after surgery, and the first three postoperative days, were analyzed. Specifically, hemoglobin (Hb, g/dL), red blood cells (RBCs, ×10(6)/μL), and hematocrit (HCT, %) trends were collected. Results: Considering the Hb trend, the median values in the preoperative day, postoperative day (POD) 2, and POD 3 are 14.7 (interquartile range (IQR) = 13.9–15.4), 12.1 (IQR = 11.2–12.9), and 12.2 (IQR = 11.2–13.1), respectively. The ∆ between preoperative day and POD 2 is 2.5 (IQR = 1.8–3.2) (p < 0.001). Considering the RBCs trend, the median values in the preoperative day, POD 2, and POD 3 are 4.9 (IQR = 4.7–5.3), 4.1 (IQR = 3.8–4.4), and 4.1 (IQR = 3.8–4.5), respectively. The ∆ between preoperative day and POD 2 is 0.9 (IQR = 0.6–1.1) (p < 0.001). Considering the HCT trend, the median values in the preoperative day, POD 2, and POD 3 are 44.4 (IQR = 41.7–46.6), 36.4 (IQR = 33.8–38.9), and 36.1 (IQR = 33.5–38.7), respectively. The ∆ between preoperative day and POD 2 is 7.8 (IQR = 5.2–10.5) (p < 0.001). Conclusions: Overall, patients undergoing RARP experience a significant, but clinically limited, decline in red line cell values between the preoperative time and the second day post-surgery. These observations are important to provide physicians with knowledge of the expected postoperative course and, thus, to improve the quality of patient care. |
format | Online Article Text |
id | pubmed-9695953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96959532022-11-26 Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer Di Bello, Francesco Di Mauro, Ernesto Collà Ruvolo, Claudia Creta, Massimiliano La Rocca, Roberto Celentano, Giuseppe Capece, Marco Napolitano, Luigi Morra, Simone Pezone, Gabriele Passaro, Francesco De Luca, Ciro Mangiapia, Francesco Logrieco, Nicola Buonanno, Pasquale Servillo, Giuseppe Imbimbo, Ciro Mirone, Vincenzo Longo, Nicola Califano, Gianluigi Medicina (Kaunas) Article Background and Objective: Blood loss represents a long-standing concern of radical prostatectomy (RP). This study aimed to assess how red line cell values changed following robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Materials and Methods: The blood panels of 453 consecutive PCa patients undergoing RARP at a single tertiary academic referral center, from September 2020 to April 2022, were reviewed. Data from 363 patients with the blood panel available for the following timeframe: within seven days before surgery, six hours after surgery, and the first three postoperative days, were analyzed. Specifically, hemoglobin (Hb, g/dL), red blood cells (RBCs, ×10(6)/μL), and hematocrit (HCT, %) trends were collected. Results: Considering the Hb trend, the median values in the preoperative day, postoperative day (POD) 2, and POD 3 are 14.7 (interquartile range (IQR) = 13.9–15.4), 12.1 (IQR = 11.2–12.9), and 12.2 (IQR = 11.2–13.1), respectively. The ∆ between preoperative day and POD 2 is 2.5 (IQR = 1.8–3.2) (p < 0.001). Considering the RBCs trend, the median values in the preoperative day, POD 2, and POD 3 are 4.9 (IQR = 4.7–5.3), 4.1 (IQR = 3.8–4.4), and 4.1 (IQR = 3.8–4.5), respectively. The ∆ between preoperative day and POD 2 is 0.9 (IQR = 0.6–1.1) (p < 0.001). Considering the HCT trend, the median values in the preoperative day, POD 2, and POD 3 are 44.4 (IQR = 41.7–46.6), 36.4 (IQR = 33.8–38.9), and 36.1 (IQR = 33.5–38.7), respectively. The ∆ between preoperative day and POD 2 is 7.8 (IQR = 5.2–10.5) (p < 0.001). Conclusions: Overall, patients undergoing RARP experience a significant, but clinically limited, decline in red line cell values between the preoperative time and the second day post-surgery. These observations are important to provide physicians with knowledge of the expected postoperative course and, thus, to improve the quality of patient care. MDPI 2022-10-25 /pmc/articles/PMC9695953/ /pubmed/36363477 http://dx.doi.org/10.3390/medicina58111520 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Di Bello, Francesco Di Mauro, Ernesto Collà Ruvolo, Claudia Creta, Massimiliano La Rocca, Roberto Celentano, Giuseppe Capece, Marco Napolitano, Luigi Morra, Simone Pezone, Gabriele Passaro, Francesco De Luca, Ciro Mangiapia, Francesco Logrieco, Nicola Buonanno, Pasquale Servillo, Giuseppe Imbimbo, Ciro Mirone, Vincenzo Longo, Nicola Califano, Gianluigi Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title | Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title_full | Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title_fullStr | Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title_full_unstemmed | Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title_short | Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer |
title_sort | perioperative red cell line trend following robot-assisted radical prostatectomy for prostate cancer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695953/ https://www.ncbi.nlm.nih.gov/pubmed/36363477 http://dx.doi.org/10.3390/medicina58111520 |
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