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LRP1-Mediated Endocytosis May Be the Main Reason for the Difference in Cytotoxicity of Curcin and Curcin C on U2OS Osteosarcoma Cells

Curcin and Curcin C, both of the ribosome-inactivating proteins of Jatropha curcas, have apparent inhibitory effects on the proliferation of osteosarcoma cell line U20S. However, the inhibitory effect of the latter is 13-fold higher than that of Curcin. The mechanism responsible for the difference h...

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Detalles Bibliográficos
Autores principales:	Qin, Siying, Wang, Xueying, Han, Pan, Lai, Zhiping, Ren, Yingying, Ma, Rui, Cheng, Cheng, Wang, Ting, Xu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695959/ https://www.ncbi.nlm.nih.gov/pubmed/36356021 http://dx.doi.org/10.3390/toxins14110771

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