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Regulatory T-Cell Enhancement, Expression of Adhesion Molecules, and Production of Anti-Inflammatory Factors Are Differentially Modulated by Spheroid-Cultured Mesenchymal Stem Cells

The culture of mesenchymal stem cells (MSCs) as spheroids promotes a more physiological cellular behavior, as it more accurately reflects the biological microenvironment. Nevertheless, mixed results have been found regarding the immunosuppressive properties of spheroid-cultured MSCs (3D-MSCs), the m...

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Detalles Bibliográficos
Autores principales: Silva-Carvalho, Amandda Évelin, da Silva, Ingrid Gracielle Martins, Corrêa, José Raimundo, Saldanha-Araujo, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695986/
https://www.ncbi.nlm.nih.gov/pubmed/36430835
http://dx.doi.org/10.3390/ijms232214349