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Insights into the Small Molecule Targeting of Biologically Relevant G-Quadruplexes: An Overview of NMR and Crystal Structures

G-quadruplexes turned out to be important targets for the development of novel targeted anticancer/antiviral therapies. More than 3000 G-quadruplex small-molecule ligands have been described, with most of them exerting anticancer/antiviral activity by inducing telomeric damage and/or altering oncoge...

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Detalles Bibliográficos
Autores principales:	Criscuolo, Andrea, Napolitano, Ettore, Riccardi, Claudia, Musumeci, Domenica, Platella, Chiara, Montesarchio, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696056/ https://www.ncbi.nlm.nih.gov/pubmed/36365179 http://dx.doi.org/10.3390/pharmaceutics14112361

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