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An Efficient UPLC-MS/MS Method for the Determination of Pyrroloquinoline Quinone in Rat Plasma and Its Application to a Toxicokinetic Study
Pyrroloquinoline quinone (PQQ) is a powerful antioxidant coenzyme existing in diet, benefiting growth, development, cognition function, and the repair of damaged organs. However, a method for detecting PQQ in vivo was rarely described, limiting the research on the bioanalysis and metabolic propertie...
Autores principales: | Sun, Qingmei, Hong, Yawen, Yang, Zhaoxu, He, Peixia, Chen, Chao, Wang, Jincheng, Weng, Qinjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696253/ https://www.ncbi.nlm.nih.gov/pubmed/36432048 http://dx.doi.org/10.3390/molecules27227947 |
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