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Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study

Hepatitis B, C, and D virus infections are a major public health problem, and Mongolia has one of the highest prevalences of dual and triple infections in the world. We aimed to determine the seroprevalence of hepatitis infection and dual or triple hepatitis infections among 10–64-year-olds. A quest...

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Autores principales: Dambadarjaa, Davaalkham, Radnaa, Otgonbayar, Khuyag, Ser-Od, Shagdarsuren, Oyu-Erdene, Enkhbayar, Uranbaigali, Mukhtar, Yerkyebulan, Tsogzolbaatar, Enkh-Oyun, Nyam, Gunchmaa, Shaarii, Shatar, Singh, Pramil, Takahashi, Masaharu, Namdag, Bira, Okamoto, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696522/
https://www.ncbi.nlm.nih.gov/pubmed/36423023
http://dx.doi.org/10.3390/vaccines10111928
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author Dambadarjaa, Davaalkham
Radnaa, Otgonbayar
Khuyag, Ser-Od
Shagdarsuren, Oyu-Erdene
Enkhbayar, Uranbaigali
Mukhtar, Yerkyebulan
Tsogzolbaatar, Enkh-Oyun
Nyam, Gunchmaa
Shaarii, Shatar
Singh, Pramil
Takahashi, Masaharu
Namdag, Bira
Okamoto, Hiroaki
author_facet Dambadarjaa, Davaalkham
Radnaa, Otgonbayar
Khuyag, Ser-Od
Shagdarsuren, Oyu-Erdene
Enkhbayar, Uranbaigali
Mukhtar, Yerkyebulan
Tsogzolbaatar, Enkh-Oyun
Nyam, Gunchmaa
Shaarii, Shatar
Singh, Pramil
Takahashi, Masaharu
Namdag, Bira
Okamoto, Hiroaki
author_sort Dambadarjaa, Davaalkham
collection PubMed
description Hepatitis B, C, and D virus infections are a major public health problem, and Mongolia has one of the highest prevalences of dual and triple infections in the world. We aimed to determine the seroprevalence of hepatitis infection and dual or triple hepatitis infections among 10–64-year-olds. A questionnaire was used to identify risk factors for hepatitis infection, and seromarkers were measured by the fully automated immunologic analyzer HISCL-5000. Among a total of 10,040 participants, 8.1% of the population aged 10–64 was infected with HBV, 9.4% with HCV, and 0.4% with HBV and HCV, and the prevalence of the disease varied by age, sex, and the area of residence. Young people were particularly unaware of their hepatitis infection status. A small proportion of children aged 10 to 19 years and the majority of adults younger than 30 years were unaware of their HBV and HCV infection. Men were also more likely to be unaware of their HBV and HCV infection status than women. The results suggested that the prevalence of infection in the general population is high and that most people are unaware that they are infected or have become chronic carriers. Identifying mono-, co-, or triple-infection status is critical to prevent the rapid progression of liver disease among the Mongolian population.
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spelling pubmed-96965222022-11-26 Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study Dambadarjaa, Davaalkham Radnaa, Otgonbayar Khuyag, Ser-Od Shagdarsuren, Oyu-Erdene Enkhbayar, Uranbaigali Mukhtar, Yerkyebulan Tsogzolbaatar, Enkh-Oyun Nyam, Gunchmaa Shaarii, Shatar Singh, Pramil Takahashi, Masaharu Namdag, Bira Okamoto, Hiroaki Vaccines (Basel) Article Hepatitis B, C, and D virus infections are a major public health problem, and Mongolia has one of the highest prevalences of dual and triple infections in the world. We aimed to determine the seroprevalence of hepatitis infection and dual or triple hepatitis infections among 10–64-year-olds. A questionnaire was used to identify risk factors for hepatitis infection, and seromarkers were measured by the fully automated immunologic analyzer HISCL-5000. Among a total of 10,040 participants, 8.1% of the population aged 10–64 was infected with HBV, 9.4% with HCV, and 0.4% with HBV and HCV, and the prevalence of the disease varied by age, sex, and the area of residence. Young people were particularly unaware of their hepatitis infection status. A small proportion of children aged 10 to 19 years and the majority of adults younger than 30 years were unaware of their HBV and HCV infection. Men were also more likely to be unaware of their HBV and HCV infection status than women. The results suggested that the prevalence of infection in the general population is high and that most people are unaware that they are infected or have become chronic carriers. Identifying mono-, co-, or triple-infection status is critical to prevent the rapid progression of liver disease among the Mongolian population. MDPI 2022-11-14 /pmc/articles/PMC9696522/ /pubmed/36423023 http://dx.doi.org/10.3390/vaccines10111928 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dambadarjaa, Davaalkham
Radnaa, Otgonbayar
Khuyag, Ser-Od
Shagdarsuren, Oyu-Erdene
Enkhbayar, Uranbaigali
Mukhtar, Yerkyebulan
Tsogzolbaatar, Enkh-Oyun
Nyam, Gunchmaa
Shaarii, Shatar
Singh, Pramil
Takahashi, Masaharu
Namdag, Bira
Okamoto, Hiroaki
Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title_full Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title_fullStr Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title_full_unstemmed Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title_short Hepatitis B, C, and D Virus Infection among Population Aged 10–64 Years in Mongolia: Baseline Survey Data of a Nationwide Cancer Cohort Study
title_sort hepatitis b, c, and d virus infection among population aged 10–64 years in mongolia: baseline survey data of a nationwide cancer cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696522/
https://www.ncbi.nlm.nih.gov/pubmed/36423023
http://dx.doi.org/10.3390/vaccines10111928
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