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Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial

Sugary soft drinks modify salivary pH and favor bacterial proliferation and are associated with the development of caries. Information on the effects of consuming carbonated drinks without sucrose is limited. Methods: In this crossover clinical trial, salivary and dental biofilm pH were determined a...

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Autores principales: Barajas-Torres, Guadalupe Carolina, Klünder-Klünder, Miguel, Garduño-Espinosa, Juan, Parra-Ortega, Israel, Franco-Hernández, María Isabel, Miranda-Lora, América Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696556/
https://www.ncbi.nlm.nih.gov/pubmed/36362931
http://dx.doi.org/10.3390/life12111776
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author Barajas-Torres, Guadalupe Carolina
Klünder-Klünder, Miguel
Garduño-Espinosa, Juan
Parra-Ortega, Israel
Franco-Hernández, María Isabel
Miranda-Lora, América Liliana
author_facet Barajas-Torres, Guadalupe Carolina
Klünder-Klünder, Miguel
Garduño-Espinosa, Juan
Parra-Ortega, Israel
Franco-Hernández, María Isabel
Miranda-Lora, América Liliana
author_sort Barajas-Torres, Guadalupe Carolina
collection PubMed
description Sugary soft drinks modify salivary pH and favor bacterial proliferation and are associated with the development of caries. Information on the effects of consuming carbonated drinks without sucrose is limited. Methods: In this crossover clinical trial, salivary and dental biofilm pH were determined at 0, 5, 10, 15, 30, 45, and 60 min after the participants (n = 18) ingested a soft drink with sucrose, a soft drink with aspartame/acesulfame K, carbonated water, and plain water on different days. Dental biofilm cultures were conducted at 0- and 120-min. Results: Salivary pH decreased significantly after ingestion of the sucrose-containing soft drink when compared with the other types of beverages (median difference, −0.3–−0.4, p ≤ 0.05), and the greatest difference was found with mineral water. A greater bacterial proliferation (Colony Forming Units [CFU]) was observed after ingestion of the drink with sucrose (↑310 × 10(3) CFU, p ≤ 0.01), followed by the drink with aspartame/acesulfame K (↑160 × 10(3) CFU, p ≤ 0.01) and carbonated water (↑60 × 10(3) CFU, p ≤ 0.05). No significant changes in bacterial proliferation were observed after the consumption of natural water. Conclusions: Ingestion of sucrose-containing soft drinks favors the acidification of salivary pH and the bacterial proliferation of dental biofilm. Although to a lesser extent, soft drinks containing aspartame/acesulfame K also favor bacterial proliferation.
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spelling pubmed-96965562022-11-26 Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial Barajas-Torres, Guadalupe Carolina Klünder-Klünder, Miguel Garduño-Espinosa, Juan Parra-Ortega, Israel Franco-Hernández, María Isabel Miranda-Lora, América Liliana Life (Basel) Article Sugary soft drinks modify salivary pH and favor bacterial proliferation and are associated with the development of caries. Information on the effects of consuming carbonated drinks without sucrose is limited. Methods: In this crossover clinical trial, salivary and dental biofilm pH were determined at 0, 5, 10, 15, 30, 45, and 60 min after the participants (n = 18) ingested a soft drink with sucrose, a soft drink with aspartame/acesulfame K, carbonated water, and plain water on different days. Dental biofilm cultures were conducted at 0- and 120-min. Results: Salivary pH decreased significantly after ingestion of the sucrose-containing soft drink when compared with the other types of beverages (median difference, −0.3–−0.4, p ≤ 0.05), and the greatest difference was found with mineral water. A greater bacterial proliferation (Colony Forming Units [CFU]) was observed after ingestion of the drink with sucrose (↑310 × 10(3) CFU, p ≤ 0.01), followed by the drink with aspartame/acesulfame K (↑160 × 10(3) CFU, p ≤ 0.01) and carbonated water (↑60 × 10(3) CFU, p ≤ 0.05). No significant changes in bacterial proliferation were observed after the consumption of natural water. Conclusions: Ingestion of sucrose-containing soft drinks favors the acidification of salivary pH and the bacterial proliferation of dental biofilm. Although to a lesser extent, soft drinks containing aspartame/acesulfame K also favor bacterial proliferation. MDPI 2022-11-03 /pmc/articles/PMC9696556/ /pubmed/36362931 http://dx.doi.org/10.3390/life12111776 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barajas-Torres, Guadalupe Carolina
Klünder-Klünder, Miguel
Garduño-Espinosa, Juan
Parra-Ortega, Israel
Franco-Hernández, María Isabel
Miranda-Lora, América Liliana
Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title_full Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title_fullStr Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title_full_unstemmed Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title_short Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
title_sort effects of carbonated beverage consumption on oral ph and bacterial proliferation in adolescents: a randomized crossover clinical trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696556/
https://www.ncbi.nlm.nih.gov/pubmed/36362931
http://dx.doi.org/10.3390/life12111776
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