A Bench-Top Approach for Isolation of Single Antibody Producing Chinese Hamster Ovary (CHO) Cells Using a Microwell-Based Microfluidic Device

Genetically-modified monoclonal cell lines are currently used for monoclonal antibody (mAbs) production and drug development. The isolation of single transformed cells is the main hindrance in the generation of monoclonal lines. Although the conventional limiting dilution method is time-consuming, l...

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Detalles Bibliográficos
Autores principales: Fuadiyah, Salma, Chotchindakun, Kittipat, Phatthanakun, Rungrueang, Kuntanawat, Panwong, Yamabhai, Montarop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696589/
https://www.ncbi.nlm.nih.gov/pubmed/36363960
http://dx.doi.org/10.3390/mi13111939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696589/
https://www.ncbi.nlm.nih.gov/pubmed/36363960
http://dx.doi.org/10.3390/mi13111939

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