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In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy

Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer patients. Despite its effectiveness, its inherent adverse toxic side effects often limit its clinical application. To overcome these drawbacks, lipid–polymer hybrid nanoparticles (LPNP) arise as promising nan...

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Detalles Bibliográficos
Autores principales: Fernandes, Renata S., Arribada, Raquel Gregório, Silva, Juliana O., Silva-Cunha, Armando, Townsend, Danyelle M., Ferreira, Lucas A. M., Barros, André L. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696591/
https://www.ncbi.nlm.nih.gov/pubmed/36365212
http://dx.doi.org/10.3390/pharmaceutics14112394

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