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In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy
Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer patients. Despite its effectiveness, its inherent adverse toxic side effects often limit its clinical application. To overcome these drawbacks, lipid–polymer hybrid nanoparticles (LPNP) arise as promising nan...
Autores principales: | Fernandes, Renata S., Arribada, Raquel Gregório, Silva, Juliana O., Silva-Cunha, Armando, Townsend, Danyelle M., Ferreira, Lucas A. M., Barros, André L. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696591/ https://www.ncbi.nlm.nih.gov/pubmed/36365212 http://dx.doi.org/10.3390/pharmaceutics14112394 |
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