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Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock

The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emerge...

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Autores principales: Ivanov, Borko, Krasivskyi, Ihor, Gerfer, Stephen, Sabashnikov, Anton, Doss, Mirko, Holzhey, David, Eghbalzadeh, Kaveh, Rustenbach, Christian, Kuhn, Elmar, Rahmanian, Parwis Baradaran, Mader, Navid, Djordjevic, Ilija, Wahlers, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696618/
https://www.ncbi.nlm.nih.gov/pubmed/36431007
http://dx.doi.org/10.3390/life12111872
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author Ivanov, Borko
Krasivskyi, Ihor
Gerfer, Stephen
Sabashnikov, Anton
Doss, Mirko
Holzhey, David
Eghbalzadeh, Kaveh
Rustenbach, Christian
Kuhn, Elmar
Rahmanian, Parwis Baradaran
Mader, Navid
Djordjevic, Ilija
Wahlers, Thorsten
author_facet Ivanov, Borko
Krasivskyi, Ihor
Gerfer, Stephen
Sabashnikov, Anton
Doss, Mirko
Holzhey, David
Eghbalzadeh, Kaveh
Rustenbach, Christian
Kuhn, Elmar
Rahmanian, Parwis Baradaran
Mader, Navid
Djordjevic, Ilija
Wahlers, Thorsten
author_sort Ivanov, Borko
collection PubMed
description The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emergent cardiac surgery procedures. Between April 2006 and October 2016, 164 consecutive patients that received VA-ECMO therapy due to PCS were identified and included in this retrospective cohort study. The patients were divided into groups based on the urgency of the initial procedures performed: elective group (ELG; n = 95) and an emergency group (EMG; n = 69). To compare the unequal patient groups, a propensity score-based matching (PSM) was applied (ELG, n = 56 vs. EMG, n = 56). The EMG primarily received ECMO intraoperatively (p ≤ 0.001). In contrast, the ELG were needed ECMO support more frequently postoperatively (p < 0.001). In-hospital mortality accounted for 71% (n = 40) in the ELG and 76% (n = 43) in the EMG (p = 0.518). Outcome data showed no major differences in the (abdominal ischemia (p = 0.371); septic shock (p = 0.393): rhythm disturbances (p = 0.575); emergency re-thoracotomy (p = 0.418)) between the groups. The urgency of the initial procedures performed is secondary in patients suffering PCS and following ECMO. In this regard, PCS itself seems to trigger outcomes in cardiac surgery ECMO patients substantially.
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spelling pubmed-96966182022-11-26 Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock Ivanov, Borko Krasivskyi, Ihor Gerfer, Stephen Sabashnikov, Anton Doss, Mirko Holzhey, David Eghbalzadeh, Kaveh Rustenbach, Christian Kuhn, Elmar Rahmanian, Parwis Baradaran Mader, Navid Djordjevic, Ilija Wahlers, Thorsten Life (Basel) Article The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emergent cardiac surgery procedures. Between April 2006 and October 2016, 164 consecutive patients that received VA-ECMO therapy due to PCS were identified and included in this retrospective cohort study. The patients were divided into groups based on the urgency of the initial procedures performed: elective group (ELG; n = 95) and an emergency group (EMG; n = 69). To compare the unequal patient groups, a propensity score-based matching (PSM) was applied (ELG, n = 56 vs. EMG, n = 56). The EMG primarily received ECMO intraoperatively (p ≤ 0.001). In contrast, the ELG were needed ECMO support more frequently postoperatively (p < 0.001). In-hospital mortality accounted for 71% (n = 40) in the ELG and 76% (n = 43) in the EMG (p = 0.518). Outcome data showed no major differences in the (abdominal ischemia (p = 0.371); septic shock (p = 0.393): rhythm disturbances (p = 0.575); emergency re-thoracotomy (p = 0.418)) between the groups. The urgency of the initial procedures performed is secondary in patients suffering PCS and following ECMO. In this regard, PCS itself seems to trigger outcomes in cardiac surgery ECMO patients substantially. MDPI 2022-11-13 /pmc/articles/PMC9696618/ /pubmed/36431007 http://dx.doi.org/10.3390/life12111872 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ivanov, Borko
Krasivskyi, Ihor
Gerfer, Stephen
Sabashnikov, Anton
Doss, Mirko
Holzhey, David
Eghbalzadeh, Kaveh
Rustenbach, Christian
Kuhn, Elmar
Rahmanian, Parwis Baradaran
Mader, Navid
Djordjevic, Ilija
Wahlers, Thorsten
Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title_full Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title_fullStr Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title_full_unstemmed Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title_short Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
title_sort impact of initial operative urgency on short-term outcomes in patients treated with ecmo due to postcardiotomy cardiogenic shock
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696618/
https://www.ncbi.nlm.nih.gov/pubmed/36431007
http://dx.doi.org/10.3390/life12111872
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