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Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock
The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emerge...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696618/ https://www.ncbi.nlm.nih.gov/pubmed/36431007 http://dx.doi.org/10.3390/life12111872 |
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author | Ivanov, Borko Krasivskyi, Ihor Gerfer, Stephen Sabashnikov, Anton Doss, Mirko Holzhey, David Eghbalzadeh, Kaveh Rustenbach, Christian Kuhn, Elmar Rahmanian, Parwis Baradaran Mader, Navid Djordjevic, Ilija Wahlers, Thorsten |
author_facet | Ivanov, Borko Krasivskyi, Ihor Gerfer, Stephen Sabashnikov, Anton Doss, Mirko Holzhey, David Eghbalzadeh, Kaveh Rustenbach, Christian Kuhn, Elmar Rahmanian, Parwis Baradaran Mader, Navid Djordjevic, Ilija Wahlers, Thorsten |
author_sort | Ivanov, Borko |
collection | PubMed |
description | The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emergent cardiac surgery procedures. Between April 2006 and October 2016, 164 consecutive patients that received VA-ECMO therapy due to PCS were identified and included in this retrospective cohort study. The patients were divided into groups based on the urgency of the initial procedures performed: elective group (ELG; n = 95) and an emergency group (EMG; n = 69). To compare the unequal patient groups, a propensity score-based matching (PSM) was applied (ELG, n = 56 vs. EMG, n = 56). The EMG primarily received ECMO intraoperatively (p ≤ 0.001). In contrast, the ELG were needed ECMO support more frequently postoperatively (p < 0.001). In-hospital mortality accounted for 71% (n = 40) in the ELG and 76% (n = 43) in the EMG (p = 0.518). Outcome data showed no major differences in the (abdominal ischemia (p = 0.371); septic shock (p = 0.393): rhythm disturbances (p = 0.575); emergency re-thoracotomy (p = 0.418)) between the groups. The urgency of the initial procedures performed is secondary in patients suffering PCS and following ECMO. In this regard, PCS itself seems to trigger outcomes in cardiac surgery ECMO patients substantially. |
format | Online Article Text |
id | pubmed-9696618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96966182022-11-26 Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock Ivanov, Borko Krasivskyi, Ihor Gerfer, Stephen Sabashnikov, Anton Doss, Mirko Holzhey, David Eghbalzadeh, Kaveh Rustenbach, Christian Kuhn, Elmar Rahmanian, Parwis Baradaran Mader, Navid Djordjevic, Ilija Wahlers, Thorsten Life (Basel) Article The outcomes of patients with PCS and following ECMO therapy are associated with several preoperative risk factors. Our aim was to compare clinical presentation, ECMO-related data and in-hospital outcomes of patients treated with ECMO due to PCS after cardiac surgery, in regard to elective or emergent cardiac surgery procedures. Between April 2006 and October 2016, 164 consecutive patients that received VA-ECMO therapy due to PCS were identified and included in this retrospective cohort study. The patients were divided into groups based on the urgency of the initial procedures performed: elective group (ELG; n = 95) and an emergency group (EMG; n = 69). To compare the unequal patient groups, a propensity score-based matching (PSM) was applied (ELG, n = 56 vs. EMG, n = 56). The EMG primarily received ECMO intraoperatively (p ≤ 0.001). In contrast, the ELG were needed ECMO support more frequently postoperatively (p < 0.001). In-hospital mortality accounted for 71% (n = 40) in the ELG and 76% (n = 43) in the EMG (p = 0.518). Outcome data showed no major differences in the (abdominal ischemia (p = 0.371); septic shock (p = 0.393): rhythm disturbances (p = 0.575); emergency re-thoracotomy (p = 0.418)) between the groups. The urgency of the initial procedures performed is secondary in patients suffering PCS and following ECMO. In this regard, PCS itself seems to trigger outcomes in cardiac surgery ECMO patients substantially. MDPI 2022-11-13 /pmc/articles/PMC9696618/ /pubmed/36431007 http://dx.doi.org/10.3390/life12111872 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ivanov, Borko Krasivskyi, Ihor Gerfer, Stephen Sabashnikov, Anton Doss, Mirko Holzhey, David Eghbalzadeh, Kaveh Rustenbach, Christian Kuhn, Elmar Rahmanian, Parwis Baradaran Mader, Navid Djordjevic, Ilija Wahlers, Thorsten Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title | Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title_full | Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title_fullStr | Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title_full_unstemmed | Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title_short | Impact of Initial Operative Urgency on Short-Term Outcomes in Patients Treated with ECMO Due to Postcardiotomy Cardiogenic Shock |
title_sort | impact of initial operative urgency on short-term outcomes in patients treated with ecmo due to postcardiotomy cardiogenic shock |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696618/ https://www.ncbi.nlm.nih.gov/pubmed/36431007 http://dx.doi.org/10.3390/life12111872 |
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