Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI)

Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease characterized by progressive loss of motor function with an average survival time of 2–5 years after diagnosis. Due to the lack of signature biomarkers and heterogenous disease phenotypes, a definitive diagnosis of...

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Detalles Bibliográficos
Autores principales: Sohn, Alexandria L., Ping, Lingyan, Glass, Jonathan D., Seyfried, Nicholas T., Hector, Emily C., Muddiman, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696666/
https://www.ncbi.nlm.nih.gov/pubmed/36355179
http://dx.doi.org/10.3390/metabo12111096

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