Cargando…

Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience

Background: Wide-necked aneurysms remain challenging for both coiling and microsurgical clipping. They often require additional techniques to prevent coil prolapse into the parent artery, such as balloon- and stent-assisted coiling. Comaneci is an expandable and removable stent that acts as a bridgi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vinacci, Gabriele, Celentano, Angelica, Agosti, Edoardo, Terrana, Alberto Vito, Vizzari, Francesco Alberto, Nativo, Luca, Baruzzi, Fabio, Tabano, Antonio, Locatelli, Davide, Giorgianni, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696797/
https://www.ncbi.nlm.nih.gov/pubmed/36431127
http://dx.doi.org/10.3390/jcm11226650
_version_ 1784838397203841024
author Vinacci, Gabriele
Celentano, Angelica
Agosti, Edoardo
Terrana, Alberto Vito
Vizzari, Francesco Alberto
Nativo, Luca
Baruzzi, Fabio
Tabano, Antonio
Locatelli, Davide
Giorgianni, Andrea
author_facet Vinacci, Gabriele
Celentano, Angelica
Agosti, Edoardo
Terrana, Alberto Vito
Vizzari, Francesco Alberto
Nativo, Luca
Baruzzi, Fabio
Tabano, Antonio
Locatelli, Davide
Giorgianni, Andrea
author_sort Vinacci, Gabriele
collection PubMed
description Background: Wide-necked aneurysms remain challenging for both coiling and microsurgical clipping. They often require additional techniques to prevent coil prolapse into the parent artery, such as balloon- and stent-assisted coiling. Comaneci is an expandable and removable stent that acts as a bridging device and does not interfere with the blood flow of the parent artery. Methods: We retrospectively reviewed our institutional radiological and clinical chart of patients treated for saccular intracranial aneurysm via endovascular Comaneci-assisted coiling. The aim of the study was to report our preliminary experience in Comaneci-assisted coiling of wide-necked intracranial aneurysms. Results: We included 14 patients in the study. Of these, 11 had a ruptured intracranial aneurysm and were treated with Comaneci-assisted coiling. We registered five minor intraprocedural complications and two intraprocedural failures of the device. At one-year follow-up, a satisfying aneurysm occlusion was observed in 85% of the cases. Conclusions: Though long-term follow-up data and larger case series are needed, this preliminary study showed the feasibility of the Comaneci-assisted coiling method for both ruptured and unruptured wide-neck intracranial aneurysms, with similar occlusion rates as balloon-assisted coiling. However, we registered high incidence of thromboembolic complications; these were probably related to the lack of heparin administration. The main advantageous application of this technique is likely in cases of ruptured intracranial aneurysms, as there is no need for post-procedural antiplatelet therapy.
format Online
Article
Text
id pubmed-9696797
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96967972022-11-26 Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience Vinacci, Gabriele Celentano, Angelica Agosti, Edoardo Terrana, Alberto Vito Vizzari, Francesco Alberto Nativo, Luca Baruzzi, Fabio Tabano, Antonio Locatelli, Davide Giorgianni, Andrea J Clin Med Article Background: Wide-necked aneurysms remain challenging for both coiling and microsurgical clipping. They often require additional techniques to prevent coil prolapse into the parent artery, such as balloon- and stent-assisted coiling. Comaneci is an expandable and removable stent that acts as a bridging device and does not interfere with the blood flow of the parent artery. Methods: We retrospectively reviewed our institutional radiological and clinical chart of patients treated for saccular intracranial aneurysm via endovascular Comaneci-assisted coiling. The aim of the study was to report our preliminary experience in Comaneci-assisted coiling of wide-necked intracranial aneurysms. Results: We included 14 patients in the study. Of these, 11 had a ruptured intracranial aneurysm and were treated with Comaneci-assisted coiling. We registered five minor intraprocedural complications and two intraprocedural failures of the device. At one-year follow-up, a satisfying aneurysm occlusion was observed in 85% of the cases. Conclusions: Though long-term follow-up data and larger case series are needed, this preliminary study showed the feasibility of the Comaneci-assisted coiling method for both ruptured and unruptured wide-neck intracranial aneurysms, with similar occlusion rates as balloon-assisted coiling. However, we registered high incidence of thromboembolic complications; these were probably related to the lack of heparin administration. The main advantageous application of this technique is likely in cases of ruptured intracranial aneurysms, as there is no need for post-procedural antiplatelet therapy. MDPI 2022-11-09 /pmc/articles/PMC9696797/ /pubmed/36431127 http://dx.doi.org/10.3390/jcm11226650 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vinacci, Gabriele
Celentano, Angelica
Agosti, Edoardo
Terrana, Alberto Vito
Vizzari, Francesco Alberto
Nativo, Luca
Baruzzi, Fabio
Tabano, Antonio
Locatelli, Davide
Giorgianni, Andrea
Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title_full Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title_fullStr Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title_full_unstemmed Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title_short Comaneci-Assisted Coiling of Wide-Necked Intracranial Aneurysm: A Single-Center Preliminary Experience
title_sort comaneci-assisted coiling of wide-necked intracranial aneurysm: a single-center preliminary experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696797/
https://www.ncbi.nlm.nih.gov/pubmed/36431127
http://dx.doi.org/10.3390/jcm11226650
work_keys_str_mv AT vinaccigabriele comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT celentanoangelica comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT agostiedoardo comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT terranaalbertovito comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT vizzarifrancescoalberto comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT nativoluca comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT baruzzifabio comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT tabanoantonio comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT locatellidavide comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience
AT giorgianniandrea comaneciassistedcoilingofwideneckedintracranialaneurysmasinglecenterpreliminaryexperience