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Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials

Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and d...

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Detalles Bibliográficos
Autores principales: Li, Yilin, Su, Yuteng, Li, Zhaoxiang, Chen, Yueyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696801/
https://www.ncbi.nlm.nih.gov/pubmed/36432982
http://dx.doi.org/10.3390/polym14224855
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author Li, Yilin
Su, Yuteng
Li, Zhaoxiang
Chen, Yueyue
author_facet Li, Yilin
Su, Yuteng
Li, Zhaoxiang
Chen, Yueyue
author_sort Li, Yilin
collection PubMed
description Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and decrease toxicity towards normal tissue by host–guest interaction. In general, chemotherapy is still common therapy for solid tumors in clinics. However, supramolecular combination therapy can overcome the limitations of the traditional single-drug chemotherapy in the laboratory findings. In this review, we summarized the combination chemotherapy, photothermal chemotherapy, and gene chemotherapy based on macrocyclic supramolecular materials. Finally, the application prospects in supramolecular combination therapy are discussed.
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spelling pubmed-96968012022-11-26 Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials Li, Yilin Su, Yuteng Li, Zhaoxiang Chen, Yueyue Polymers (Basel) Review Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and decrease toxicity towards normal tissue by host–guest interaction. In general, chemotherapy is still common therapy for solid tumors in clinics. However, supramolecular combination therapy can overcome the limitations of the traditional single-drug chemotherapy in the laboratory findings. In this review, we summarized the combination chemotherapy, photothermal chemotherapy, and gene chemotherapy based on macrocyclic supramolecular materials. Finally, the application prospects in supramolecular combination therapy are discussed. MDPI 2022-11-11 /pmc/articles/PMC9696801/ /pubmed/36432982 http://dx.doi.org/10.3390/polym14224855 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Yilin
Su, Yuteng
Li, Zhaoxiang
Chen, Yueyue
Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title_full Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title_fullStr Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title_full_unstemmed Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title_short Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
title_sort supramolecular combination cancer therapy based on macrocyclic supramolecular materials
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696801/
https://www.ncbi.nlm.nih.gov/pubmed/36432982
http://dx.doi.org/10.3390/polym14224855
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AT chenyueyue supramolecularcombinationcancertherapybasedonmacrocyclicsupramolecularmaterials