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Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials
Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696801/ https://www.ncbi.nlm.nih.gov/pubmed/36432982 http://dx.doi.org/10.3390/polym14224855 |
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author | Li, Yilin Su, Yuteng Li, Zhaoxiang Chen, Yueyue |
author_facet | Li, Yilin Su, Yuteng Li, Zhaoxiang Chen, Yueyue |
author_sort | Li, Yilin |
collection | PubMed |
description | Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and decrease toxicity towards normal tissue by host–guest interaction. In general, chemotherapy is still common therapy for solid tumors in clinics. However, supramolecular combination therapy can overcome the limitations of the traditional single-drug chemotherapy in the laboratory findings. In this review, we summarized the combination chemotherapy, photothermal chemotherapy, and gene chemotherapy based on macrocyclic supramolecular materials. Finally, the application prospects in supramolecular combination therapy are discussed. |
format | Online Article Text |
id | pubmed-9696801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96968012022-11-26 Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials Li, Yilin Su, Yuteng Li, Zhaoxiang Chen, Yueyue Polymers (Basel) Review Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and decrease toxicity towards normal tissue by host–guest interaction. In general, chemotherapy is still common therapy for solid tumors in clinics. However, supramolecular combination therapy can overcome the limitations of the traditional single-drug chemotherapy in the laboratory findings. In this review, we summarized the combination chemotherapy, photothermal chemotherapy, and gene chemotherapy based on macrocyclic supramolecular materials. Finally, the application prospects in supramolecular combination therapy are discussed. MDPI 2022-11-11 /pmc/articles/PMC9696801/ /pubmed/36432982 http://dx.doi.org/10.3390/polym14224855 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Li, Yilin Su, Yuteng Li, Zhaoxiang Chen, Yueyue Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title | Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title_full | Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title_fullStr | Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title_full_unstemmed | Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title_short | Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials |
title_sort | supramolecular combination cancer therapy based on macrocyclic supramolecular materials |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696801/ https://www.ncbi.nlm.nih.gov/pubmed/36432982 http://dx.doi.org/10.3390/polym14224855 |
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