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Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia

Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortal...

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Detalles Bibliográficos
Autores principales: Thatchanamoorthy, Nishanthinie, Rukumani Devi, Velayuthan, Chandramathi, Samudi, Tay, Sun Tee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696804/
https://www.ncbi.nlm.nih.gov/pubmed/36354893
http://dx.doi.org/10.3390/jof8111126
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author Thatchanamoorthy, Nishanthinie
Rukumani Devi, Velayuthan
Chandramathi, Samudi
Tay, Sun Tee
author_facet Thatchanamoorthy, Nishanthinie
Rukumani Devi, Velayuthan
Chandramathi, Samudi
Tay, Sun Tee
author_sort Thatchanamoorthy, Nishanthinie
collection PubMed
description Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortality rates in healthcare facilities worldwide. Since its first isolation, the occurrence of C. auris in six continents has becomes a grave concern for the healthcare professionals and scientific community. Recent reports showed the identification of five geographically distinct clades and high rates of antifungal resistance associated with C. auris. Till date, there are no effective treatment options, and standardized measures for prevention and control of C. auris infection in healthcare facilities. This leads to frequent therapeutic failures and complicates the eradication of C. auris infection in healthcare facilities. Thus, this review focuses on the recent understanding of the epidemiology, risk factors, diagnosis, transmission and prevention and control strategies of C. auris infection in healthcare facilities in Asia.
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spelling pubmed-96968042022-11-26 Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia Thatchanamoorthy, Nishanthinie Rukumani Devi, Velayuthan Chandramathi, Samudi Tay, Sun Tee J Fungi (Basel) Review Candida auris, a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortality rates in healthcare facilities worldwide. Since its first isolation, the occurrence of C. auris in six continents has becomes a grave concern for the healthcare professionals and scientific community. Recent reports showed the identification of five geographically distinct clades and high rates of antifungal resistance associated with C. auris. Till date, there are no effective treatment options, and standardized measures for prevention and control of C. auris infection in healthcare facilities. This leads to frequent therapeutic failures and complicates the eradication of C. auris infection in healthcare facilities. Thus, this review focuses on the recent understanding of the epidemiology, risk factors, diagnosis, transmission and prevention and control strategies of C. auris infection in healthcare facilities in Asia. MDPI 2022-10-26 /pmc/articles/PMC9696804/ /pubmed/36354893 http://dx.doi.org/10.3390/jof8111126 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Thatchanamoorthy, Nishanthinie
Rukumani Devi, Velayuthan
Chandramathi, Samudi
Tay, Sun Tee
Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title_full Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title_fullStr Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title_full_unstemmed Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title_short Candida auris: A Mini Review on Epidemiology in Healthcare Facilities in Asia
title_sort candida auris: a mini review on epidemiology in healthcare facilities in asia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696804/
https://www.ncbi.nlm.nih.gov/pubmed/36354893
http://dx.doi.org/10.3390/jof8111126
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